Results 111 to 120 of about 52,950,106 (199)

Bactericidal synergism between phage endolysin Ply2660 and cathelicidin LL-37 against vancomycin-resistant Enterococcus faecalis biofilms. [PDF]

NPJ Biofilms Microbiomes, 2023
Zhang H, Zhang X, Liang S, Wang J, Zhu Y, Zhang W, Liu S, Schwarz S, Xie F.   +8 more
europepmc   +1 more source

Cathelicidin LL-37 Level in Leprosy Patients and Household Contacts - A Systematic Review [PDF]

Cathelicidin LL-37 is a multifunctional antimicrobial peptide central to innate immunity. Its dysregulated expression in leprosy patients and household contacts suggests a significant role in pathogenesis and potential as a prognostic biomarker.
Nur Hasira Mustakim
core  

Between good and evil:Complexation of the human cathelicidin LL-37 with nucleic acids [PDF]

The innate immune system provides a crucial first line of defense against invading pathogens attacking the body. As the only member of the human cathelicidin family, the antimicrobial peptide LL-37 has been shown to have antiviral, antifungal, and ...
Lin, Jennifer S., Barron, Annelise E., Zielke, Claudia, Nielsen, Josefine Eilsø   +3 more
core   +1 more source

Sphingosine-1-Phosphate-Triggered Expression of Cathelicidin LL-37 Promotes the Growth of Human Bladder Cancer Cells. [PDF]

Int J Mol Sci, 2022
Wollny T, Wnorowska U, Piktel E, Suprewicz Ł, Król G, Głuszek K, Góźdź S, Kopczyński J, Bucki R.   +8 more
europepmc   +1 more source

Cathelicidin LL-37 improves bone metabolic balance in rats with ovariectomy-induced osteoporosis via the Wnt/beta-catenin pathway. [PDF]

Physiol Res, 2022
Liang J, Chen J, Ye Z, Bao D.
europepmc   +1 more source

Human Cathelicidin (LL-37), a Multifunctional Peptide, is Expressed by Ocular Surface Epithelia and has Potent Antibacterial and Antiviral Activity

, 2005
Purpose: This study determined whether LL-37 (cathelicidin) is expressed by conjunctival and corneal epithelia as part of ocular host defense.
Romanowski, Eric, Huang, Ling C., Gordon, Y. Jerold, McDermott, Alison, Yates, Kathleen, Proske, Rita   +5 more
core   +1 more source

Antimicrobial peptide LL-37 increases rhinovirus-induced interferon β expression in human airway epithelial cells through a Ca2+-dependent mechanism

Biochemistry and Biophysics Reports
The human cathelicidin LL-37 is active against both bacteria and viruses, but it also shows immunomodulatory properties. Here, we assess the impact of LL-37 on viral signaling in human airway epithelial BEAS-2B cells infected with the respiratory ...
Samuel Cerps, Sangeetha Ramu, Olof Gidlöf, Mandy Menzel, Karl Swärd, Lena Uller, Bengt-Olof Nilsson   +6 more
doaj   +1 more source

Exploring the role of cathelicidin LL-37 and ceragenins in wound healing processes

European Journal of Pharmacology
Wound healing and tissue regeneration are essential for maintaining skin integrity in the face of mechanical, chemical, or thermal damage. In adult mammals, the wound healing process may include complications leading to chronic wounds and hypertrophic scars.
Łuckiewicz, Milena, Urszula Wnorowska, Zakrzewska, Magdalena, Błażejczyk, Idalia, Tamara Daniluk, Kondziołka, Wioleta, Savage, Paul, Robert Bucki, Ewelina Piktel   +8 more
openaire   +3 more sources

The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human lung,
Simpson AJ; Barlow PG; Cosseau C; Beaumont PE; Mackellar A; Wilkinson TS; Hancock REW; Govan JRW; Haslett C; Davidson DJ
core   +3 more sources

Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors. [PDF]

J Biol Chem, 2021
Kulkarni NN, O'Neill AM, Dokoshi T, Luo EWC, Wong GCL, Gallo RL.   +5 more
europepmc   +1 more source