Periodontology 2000, EarlyView.AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source
Downregulation of Cathepsin B expression alleviates periodontitis by reducing mitochondrial reactive oxygen species production and NOD-, LRR-, and pyrin domain-containing 3 -mediated pyroptosis. [PDF]
Front ImmunolWang T +8 more
europepmc +1 more source
Periodontology 2000, EarlyView.Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci +2 more
wiley +1 more source
Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success. [PDF]
Nat CommunBird LE +8 more
europepmc +1 more source
Long‐term stability of sinus complication management
Periodontology 2000, EarlyView.Abstract Maxillary sinus augmentation shows a low incidence of complications and high clinical success due to favorable biological conditions and typically transient issues. Most complications are intraoperative, such as Schneiderian membrane perforation or hemorrhage, and are often resolved immediately.
Pablo Galindo‐Moreno +5 more
wiley +1 more source
Cathepsin B in urological tumors: unraveling its role and therapeutic potential. [PDF]
Discov OncolYan Z +5 more
europepmc +1 more source
Understanding exosomes in facial esthetics and skin aging
Periodontology 2000, EarlyView.Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron +3 more
wiley +1 more source
Cathepsin B as a potential serum biomarker for early diagnosis and progression of diabetic foot ulcer complicated with peripheral vascular disease. [PDF]
Sci RepJin Y +9 more
europepmc +1 more source
Mapping the omics landscape for peri‐implant diseases: A scoping review
Periodontology 2000, EarlyView.Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng +5 more
wiley +1 more source
High-dose treatment of cathepsin B-activatable doxorubicin prodrug nanoparticles that induce tumor-specific immunogenic cell death for immunotherapy of melanoma with minimal systemic toxicity. [PDF]
Asian J Pharm SciOh Y +10 more
europepmc +1 more source