Results 51 to 60 of about 12,525,351 (366)
Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]
, 2007 rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis +7 more
core +1 more source
Journal of Immunological Research, 2018 We recently have proved that excessive fecal DCA caused by high-fat diet may serve as an endogenous danger-associated molecular pattern to activate NLRP3 inflammasome and thus contributes to the development of inflammatory bowel disease (IBD).
Shengnan Zhao +9 more
semanticscholar +1 more source
Parasites & Vectors, 2019 Background Three main enzymes including cathepsin B, cathepsin D and acid phosphatase are involved in vitellin degradation, which is a major biochemical event of the embryonic development and can provide nutrients and metabolites for tick embryos. In the
Tian-Tian Zhang +6 more
doaj +1 more source
Characterisation of Cathepsin B and Collagenolytic Cathepsin from Human Placenta [PDF]
European Journal of Biochemistry, 1978 1. Human placental cathepsin B and collagenolytic cathepsin were separated by chromatography on columns of Amberlite CG-50. Collagenolytic cathepsin was partially purified by chromatography on DEAE-Sephadex (A-50) and Sephadex G-100. Cathepsin B was purified by chromatography on CM-cellulose and Sephadex G-100. 2.
P, Evans, D J, Etherington
openaire +2 more sources
Cell Proliferation, 2018 The non‐canonical inflammasome pathway was described which engages caspase‐11 to mediate pyroptosis and the subsequent release of IL‐1α, IL‐1β and IL‐18 in TLR4‐independent way.
Nan Chen +5 more
semanticscholar +1 more source
Cathepsin B Is Implicated in Triglyceride (TG)-Induced Cell Death of Macrophage
Korean Journal of Clinical Laboratory Science, 2020 Macrophage cell death contributes to the formation of plaque, leading to the development of atherosclerosis. The accumulation of triglyceride (TG) is also associated with the pathogenesis of atherosclerosis.
Byung Chul Jung +3 more
doaj +1 more source
Cathepsin B gene disruption induced Leishmania donovani proteome remodeling implies cathepsin B role in secretome regulation. [PDF]
PLoS ONE, 2013 Leishmania cysteine proteases are potential vaccine candidates and drug targets. To study the role of cathepsin B cysteine protease, we have generated and characterized cathepsin B null mutant L. donovani parasites. L.
Teklu Kuru Gerbaba, Lashitew Gedamu
doaj +1 more source
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]
, 2012 The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Bunsen, Thea +3 more
core +1 more source
A bioavailable cathepsin S nitrile inhibitor abrogates tumor development [PDF]
, 2016 BACKGROUND: Cathepsin S has been implicated in a variety of malignancies with genetic ablation studies demonstrating a key role in tumor invasion and neo-angiogenesis.
Burden, Roberta E +4 more
core +1 more source
New Phytologist, 2017 Summary Programmed cell death (PCD) induced by endoplasmic reticulum (ER) stress is implicated in various plant physiological processes, yet its mechanism is still elusive.
Yaomin Cai +4 more
semanticscholar +1 more source