Results 121 to 130 of about 66,677 (282)

Itch and autophagy-mediated NF-κB activation contributes to inhibition of cathepsin D-induced sensitizing effect on anticancer drugs

, 2022
Seung Un Seo, Seon Min Woo, Kyoung‐jin Min, Taeg Kyu Kwon   +3 more
openalex   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Cathepsin D-like activity from embryo of camel tick Hyalomma dromedarii

(Acari: Ixodida)

Persian Journal of Acarology
It is well known that cathepsin D (CD) has a fundamental role in the degradation of yolk proteins during embryo development as it has a dual function in embryo feeding and defending against pathogens.
Mohamed S. Helmy, Hassan M.M. Masoud, Doaa A. Darwish, Mohamed M. Abdel-Monsef, Mahmoud A. Ibrahim   +4 more
doaj   +1 more source

Immuno-electron microscopical demonstration of lysosomes in human blood platelets and megakaryocytes using anti-cathepsin D [PDF]

, 1985
JJ Sixma, Albert van den Berg, Andrej Hasilík, Kurt Von Figura, H J Geuze   +4 more
openalex   +1 more source

Effect of calcium chloride injection and freezing prior to wet aging on the meat quality of cull cows

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND In Brazil, the slaughter of female cattle, particularly older animals, has increased substantially. However, meat from this category presents limitations in terms of quality, mainly because of its toughness resulting from a high concentration of cross‐links between collagen fibers.
Juliano CC Belmonte, Taynara S Santana, Micheline F Castro, Rosileide V Rohod, Marcelo Vedovatto, Aylpy RD Santos, Henrique J Fernandes, Dalton M Oliveira   +7 more
wiley   +1 more source

Involvement of cathepsins E (CE) and D (CD) in age-related neurodegenerative process developed in SAMP8 and SAMPIO mice.

, 1994
Tutomu Amano, Hiroshi Nakanishi, Kenji Yamamoto   +2 more
openalex   +1 more source

Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice [PDF]

, 2017
Shaowu Cheng, Willayat Yousuf Wani, David A. Hottman, Angela Jeong, Dongfeng Cao, Kyle J. LeBlanc, Paul Säftig, Jianhua Zhang, Ling Li   +8 more
openalex   +1 more source

The Proteomic Profiling of Circulating Extracellular Vesicles of Western Diet and Chemical‐Induced Murine MASH Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an increasingly prevalent chronic liver condition that can progress to severe complications such as metabolic dysfunction‐associated steatohepatitis (MASH). Despite its growing burden, there are no reliable non‐invasive biomarkers for tracking disease progression.
Szu‐Jen Wang, Yung‐Ho Wang, Jee‐Fu Huang, En‐Sheng Lin, Wei‐Shiun Chen, Chia‐Yang Li, Chia‐Yen Dai, Wan‐Long Chuang, Ming‐Lung Yu, Shu‐Chi Wang   +9 more
wiley   +1 more source

Supplementary Figure 3 from Cathepsin D and Eukaryotic Translation Elongation Factor 1 as Promising Markers of Cellular Senescence [PDF]

, 2023
Hae‐Ok Byun, Na‐Kyung Han, Hae‐June Lee, Kibum Kim, Young‐Gyu Ko, Gyesoon Yoon, Yun‐Sil Lee, Seok‐Il Hong, Jae‐Seon Lee   +8 more
openalex   +1 more source

Antimicrobial Cyclic Peptidomimetics

Macromolecular Rapid Communications, EarlyView.
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley   +1 more source