Results 181 to 190 of about 113,729 (277)

Sustained release of cathepsin D/cathepsin K from injectable hydrogel microspheres in anti-photoaging. [PDF]

Mater Today Bio
Hou W, Lin Z, Chen X, Sun Y, Lin Y, Peng M, Zhou F, Jiang H, Li Y, Zheng Y.   +9 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins. [PDF]

Cell Death Dis
Jiang H, Wang Y, Wang C, Yang L, Wang S, Wang F, Xue S, Zhang Z, Fu H, Dong T, Yuan J, Li Z, Li K.   +12 more
europepmc   +1 more source

Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals. [PDF]

Proc Natl Acad Sci U S A, 2022
Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi CR.   +7 more
europepmc   +1 more source

Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]

, 2018
Bukowska-Straková, Karolina, Dulak, Józef, Florczyk-Soluch, Urszula, Józefczuk, Ewelina, Józkowicz, Alicja, Mendel, Mateusz, Nowak, Witold, Stępniewski, Jacek, Viscardi, Monika   +8 more
core   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

A Dual-Function "TRE-Lox" System for Genetic Deletion or Reversible, Titratable, and Near-Complete Downregulation of Cathepsin D. [PDF]

Int J Mol Sci, 2023
Terron HM, Maranan DS, Burgard LA, LaFerla FM, Lane S, Leissring MA.   +5 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Cathepsin-D and outcomes in peripartum cardiomyopathy: Results from IPAC. [PDF]

Am Heart J Plus
Polsinelli VB, Hanley-Yanez K, McTiernan CF, Modi K, Haythe J, Skopicki H, Elkayam U, Cooper LT, Fett JD, McNamara DM, IPAC investigators.   +10 more
europepmc   +1 more source

Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication

Molecular Microbiology, EarlyView.
Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic environments within the macrophage enhances bacterial viability emphasising the role of acidic pH during NTM infections.
Parise K. Lockwood, Luiz Pedro Sorio de Carvalho, Rachel P. J. Lai, Maximiliano G. Gutierrez   +3 more
wiley   +1 more source