Results 191 to 200 of about 108,576 (328)

The role of lysosomal cysteine proteinases as markers of macrophage activation and as non-specific mediators of inflammation [PDF]

, 1993
Assfalg-Machleidt, Irmgard, Billing, A., Faist, E., Fröhlich, D., Jochum, Marianne, Joka, T., Machleidt, W., Meakins, J., Nast-Kolb, Dieter, Schildberg, F. W.   +9 more
core   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source

Actin proteolysis during ripening of dry fermented sausages at different pH values [PDF]

, 2017
Berardo, Alberto, De Maere, H, De Smet, Stefaan, Devreese, Bart, Leroy, F, Stavropoulou, DA, Van Royen, G   +6 more
core   +1 more source

Biomodification of dentin collagen with hydroalcoholic propolis extract: Impact on resin–dentin adhesion

European Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the effect of hydroalcoholic propolis extract (HPE) as a collagen cross‐linking agent for preserving the dentin–adhesive interface. Dentin beams from human third molars were demineralized with 10% phosphoric acid and assigned to five treatments: distilled water (control), 6.5% grape seed extract (GSE), and HPE at ...
Zidane Hurtado Rabelo, Edinaldo Gomes de Meneses Neto, Israel Simon Andrade Costa, Juliano Sartori Mendonça, Vanara Florêncio Passos, Sérgio Lima Santiago   +5 more
wiley   +1 more source

The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L [PDF]

, 2004
Michael Soukenik, Anne Diehl, Martina Leidert, Volker Sievert, Konrad Büssow, Dietmar Leitner, Dirk Labudde, Linda Ball, Annette Lechner, Dorit K. Nägler, Hartmut Oschkinat   +10 more
openalex   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Single-dose cathepsin L CRISPR nanotherapy mitigates PASC-like lung damage in hamsters. [PDF]

Nano Res
Cui Z, Liu T, Bacon R, Zhao Y, Everitt JI, Yan J, Chen L, Huang J, Wang H, Dong Y, Jin VX, Liu SL, Wang Q.   +12 more
europepmc   +1 more source

Cathepsin L maturation and activity is impaired in macrophages harboring M. avium and M. tuberculosis [PDF]

, 2006
Rajeev M. Nepal, Stephanie Mampe, Brian C. Shaffer, Ann H. Erickson, Paula Wolf Bryant   +4 more
openalex   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

The functional of cathepsin L in the ontogenesis and reproductive regulation of the Asian corn borer, Ostrinia furnacalis. [PDF]

Sci Rep
Zhang JS, Li J, Meng JY, Tang X, Saddique H, Zhang CY.   +5 more
europepmc   +1 more source