Results 191 to 200 of about 16,299,323 (310)

Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication

Molecular Microbiology, EarlyView.
Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic environments within the macrophage enhances bacterial viability emphasising the role of acidic pH during NTM infections.
Parise K. Lockwood, Luiz Pedro Sorio de Carvalho, Rachel P. J. Lai, Maximiliano G. Gutierrez   +3 more
wiley   +1 more source

Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer. [PDF]

World J Gastroenterol
Xiao LX, Li XJ, Yu HY, Qiu RJ, Zhai ZY, Ding WF, Zhu MS, Zhong W, Fang CF, Yang J, Chen T, Yu J.   +11 more
europepmc   +1 more source

Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding

Oral Diseases, EarlyView.
ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior, Clovis Bergamin Griso, Amanda Borges Pirondi, Laura Teodoro de Marchi, Talita Mendes Oliveira Ventura, Larissa Tercilia Grizzo, Roosevelt da Silva Bastos, Alejandra Chaparro, Nagihan Bostanci, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source

Cathepsin L induces cellular senescence by upregulating CUX1 and p16^INK4a. [PDF]

Aging (Albany NY)
Wu Y, Jiang D, Liu Q, Yan S, Liu X, Wu T, Sun W, Li G.   +7 more
europepmc   +1 more source

Psyllid Cysteine Cathepsins Directly Cleave the Outer Membrane Protein BamD of Citrus Huanglongbing Pathogen

Plant Biotechnology Journal, EarlyView.
ABSTRACT Candidatus Liberibacter asiaticus (CLas), the causative agent of citrus Huanglongbing (HLB), is transmitted by Asian citrus psyllid, Diaphorina citri; however, the role of the insect's immune effectors in defending against CLas remains poorly understood. This study reveals that D.
Yu Du, Yu Bin, Jinhua Yang, Manman Hu, Liqin Jiang, Qiaoling Su, Shiyi Lin, Lanfeng Qu, You Li, Taiyun Wei   +9 more
wiley   +1 more source

Cathepsin L in Lung Adenocarcinoma: Prognostic Significance and Immunotherapy Response Through a Multi Omics Perspective. [PDF]

Cancer Inform
Lu J, Liang J, Xiao G, He Z, Yu G, Zhang L, Cai C, Yi G, Xie J.   +8 more
europepmc   +1 more source

Assessment of serum granulysin and cathepsin-L levels in vitiligo patients. [PDF]

Rev Assoc Med Bras (1992)
Yazar C, Akbayrak A, Ozmen ZC, Kuyucu YE, Sencan M, Kutlu O, Seckin HY.   +6 more
europepmc   +1 more source

Elevated N-glycosylated cathepsin L impairs oocyte function and contributes to oocyte senescence during reproductive aging. [PDF]

Aging Cell
Zhang K, Xu R, Zheng L, Zhang H, Qian Z, Li C, Xue M, He Z, Ma J, Li Z, Chen L, Ma R, Yao B.   +12 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

Journal of Natural Products, 2014
Bailey W. Miller, Aaron J. Friedman, Hyukjae Choi, J. Hogan, J. McCammon, V. Hook, W. Gerwick   +6 more
semanticscholar   +1 more source