Results 241 to 250 of about 29,235,414 (292)

Hyperglycemia-induced cathepsin L maturation: Linking to diabetic comorbidities and COVID-19 mortality

, 2023
He Q, Zhao M, Li M, Li X, Jin J, Feng Y, Zhang L, Huang W, Yang F, Yang J.   +9 more
europepmc   +1 more source

Long‐term stability of sinus complication management

Periodontology 2000, EarlyView.
Abstract Maxillary sinus augmentation shows a low incidence of complications and high clinical success due to favorable biological conditions and typically transient issues. Most complications are intraoperative, such as Schneiderian membrane perforation or hemorrhage, and are often resolved immediately.
Pablo Galindo‐Moreno, Tiziano Testori, Miguel Padial‐Molina, Allinson Olaechea, Francisco O'Valle, Pablo Galindo‐Fernandez   +5 more
wiley   +1 more source

Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin. [PDF]

Virus Res
Mao B, Le-Trilling VTK, Tang H, Hu J, Schmitz MS, Barbet K, Xu D, Wei Z, Guo B, Mennerich D, Yao C, Liu J, Li Z, Wan Y, Zhang X, Wang K, Tang N, Yu Z, Trilling M, Lin Y.   +19 more
europepmc   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

A Novel Cystatin Gene from Sea Cucumber (<i>Apostichopus japonicus</i>): Characterization and Comparative Expression with Cathepsin L During Early Stage of Hypoxic Exposure-Induced Autolysis. [PDF]

Foods
Yao S, Zhang R, Ma S, Zhao T, Liu Q, Zhu L, Liu C, Sun L, Du M.   +8 more
europepmc   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents. [PDF]

J Am Chem Soc
Kumar V, Zhu J, Chenna BC, Hoffpauir ZA, Rademacher A, Rogers AM, Tseng CT, Drelich A, Farzandh S, Lamb AL, Meek TD.   +10 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Discovering novel Cathepsin L inhibitors from natural products using artificial intelligence. [PDF]

Comput Struct Biotechnol J
Li Q, Zhou SR, Kim H, Wang H, Zhu JJ, Yang JK.   +5 more
europepmc   +1 more source

Beyond biologic sex: Exploratory insights into the heterogeneity of hormonal and contextual drivers of periodontal and peri‐implant outcomes

Periodontology 2000, EarlyView.
Abstract Background Periodontal and peri‐implant diseases are multifactorial inflammatory conditions influenced by microbial, host, hormonal, genetic, and behavioral factors. Although sex‐based differences in immune and inflammatory responses are well recognized in medicine, the extent to which biologic sex and hormonal status influence the prevalence,
Caitlin Neapole, Mark Gettas, Roberto Farina, Yvonne Hernandez‐Kapila   +3 more
wiley   +1 more source