Results 251 to 260 of about 29,235,414 (292)

Evaluation of Reproductive Histology Response of Adult Fasciola hepatica in Goats Vaccinated with Cathepsin L Phage-Exposed Mimotopes. [PDF]

Int J Mol Sci
Villa-Mancera A, Maldonado-Hidalgo J, Robles-Robles M, Olivares-Pérez J, Olmedo-Juárez A, Rodríguez-Castillo J, Pérez-Mendoza N, Utrera-Quintana F, Pérez J, Ortega-Vargas S.   +9 more
europepmc   +1 more source

Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis, Davi Araújo, Asaf Wilensky, Juliana Girón Bastidas, Stella Alimperti, Flavia Pirih   +5 more
wiley   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury. [PDF]

iScience
Yang S, Chen K, Yu J, Jin Z, Zhang M, Li Z, Yu Y, Xuan N, Tian B, Li N, Mao Z, Wang W, Chen T, Wu Y, Zhao Y, Zhang M, Fei X, Ying S, Li W, Yan F, Zhang X, Zhang G, Shen H, Chen Z.   +23 more
europepmc   +1 more source

Clinically relevant intra‐articular corticosteroid doses impair equine osteoclast function in vitro

Veterinary Surgery, EarlyView.
Abstract Objective To assess the effects of clinically relevant doses of commonly employed intra‐articular corticosteroids—specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)—on equine osteoclasts.
Gwladys Malek, Louis Kamus, Hélène Richard, Guy Beauchamp, Sheila Laverty   +4 more
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Cathepsin L regulates oocyte meiosis and preimplantation embryo development. [PDF]

Cell Prolif
Ezz MA, Takahashi M, Rivera RM, Balboula AZ.   +3 more
europepmc   +1 more source

Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage. [PDF]

Virus Res
Bestle D, Bittel L, Werner AD, Kämper L, Dolnik O, Krähling V, Steinmetzer T, Böttcher-Friebertshäuser E.   +7 more
europepmc   +1 more source