Results 31 to 40 of about 29,235,414 (292)

Involvement of cathepsin B in the plant disease resistance hypersensitive response [PDF]

, 2007
A diverse range of plant proteases are implicated in pathogen perception and in subsequent signalling and execution of disease resistance. We demonstrate, using protease inhibitors and virus-induced gene silencing (VIGS), that the plant papain cysteine ...
Shaw, Jane, Hein, I., Christophe Lacomme, Kaffarnik, Florian, Hein, Ingo, Lopez, Eduardo C., Eduard Venter, Van Der Hoorn, Renier, Paul R. J. Birch, Pritchard, L., Borras-Hidalgo, Orlando, Hazel McLellan, Gilroy, Eleanor M., McLellan, H., Eleanor M. Gilroy, Hrubikova, Katarina, Birch, P., Orlando Borras-Hidalgo, Boevink, P., Eduardo C. López, Shaw, J., Maria Holeva, Jane Shaw, Loake, Gary J., Hrubikova, K., Katarina Hrubikova, Boevink, Petra C., Holeva, Maria, Venter, Eduard, Kaffarnik, F., McLellan, Hazel, Van der Hoorn, R., Venter, E., Lopez, E., Gary J. Loake, Hein, Ingo; id_orcid, Florian Kaffarnik, Renier Van Der Hoorn, Birch, Paul R. J.; id_orcid, Lacomme, Christophe, Loake, G., Borras-Hidalgo, O., Pritchard, Leighton, Lacomme, C., Ingo Hein, Birch, Paul R. J., Leighton Pritchard, Holeva, M., Gilroy, E., Petra C. Boevink   +49 more
core   +1 more source

Role of Endogenous Cathepsin L in Muscle Protein Degradation in Olive Flounder (Paralichthys olivaceus) Surimi Gel

Molecules, 2021
We investigated the effect of endogenous cathepsin L on surimi gel produced from olive flounder (Paralichthys olivaceus). The amino acid sequences of six proteins predicted or identified as cathepsin L were obtained from the olive flounder genome ...
Chang Woo Kwon, Pahn-Shick Chang
doaj   +1 more source

Cathepsin L is required for ecotropic murine leukemia virus infection in NIH3T3 cells. [PDF]

, 2009
Recently it has been reported that a cathepsin B inhibitor, CA-074Me, attenuates ecotropic murine leukemia virus (Eco-MLV) infection in NIH3T3 cells, suggesting that cathepsin B is required for the Eco-MLV infection.
Oishi, Kazunori, Yamamoto, Naoki, Tsutomu Mizota, Kazunori Oishi, Nobuhiko Katunuma, Kensuke Goto, Minematsu, Kazuo, Goto, Kensuke, Haruka Kamiyama, Naoki Yamamoto, Hiroaki Yoshii, Kubo, Yoshinao, Katunuma, Nobuhiko, Yoshii, Hiroaki, Kamiyama, Haruka, Mizota, Tsutomu, Kazuo Minematsu, Yoshinao Kubo   +17 more
core   +1 more source

Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis

Respiratory Research, 2011
Background Remodeling of lung tissues during the process of granuloma formation requires significant restructuring of the extra-cellular matrix and cathepsins K, L and S are among the strongest extra-cellular matrix degrading enzymes.
Percival M David, Gauthier Jacques, Samokhin Andriy O, Brömme Dieter   +3 more
doaj   +1 more source

Cathepsin B gene disruption induced Leishmania donovani proteome remodeling implies cathepsin B role in secretome regulation. [PDF]

PLoS ONE, 2013
Leishmania cysteine proteases are potential vaccine candidates and drug targets. To study the role of cathepsin B cysteine protease, we have generated and characterized cathepsin B null mutant L. donovani parasites. L.
Teklu Kuru Gerbaba, Lashitew Gedamu
doaj   +1 more source

Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]

, 2013
Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C, Mottram Jeremy C., Richard J Marhöfer, Schröder Jörg, Selzer, P.M., Schroder, J., Noack, Sandra, Noack Sandra, Schröder, Jörg, Noack, S., Mottram, J.C., Sandra Noack, Coombs, G.H., Coombs, Graham H, Marhöfer, Richard J, Coombs Graham H., Paul M Selzer, Jeremy C Mottram, Marhöfer Richard J., Marhofer, R.J., Jörg Schröder, Selzer Paul M., Selzer, Paul M, Selzer, Paul M., Graham H Coombs   +24 more
core   +4 more sources

Expression of Cathepsin L in tumor cells and tumor-associated macrophages in patients with Ewing sarcoma family of tumors: A pilot study

Indian Journal of Pathology and Microbiology, 2015
Background: Cysteine protease Cathepsin L is involved in bone remodeling and expressed in activated macrophages. It is highly expressed in metastatic tumor tissue, especially with bone metastases.
Bivas Biswas, Mehar Chand Sharma, Asit Ranjan Mridha, Sameer Bakhshi   +3 more
doaj   +1 more source

Cathepsin L plays a role in quinolinic acid-induced NF-Κb activation and excitotoxicity in rat striatal neurons. [PDF]

PLoS ONE, 2013
The present study seeks to investigate the role of cathepsin L in glutamate receptor-induced transcription factor nuclear factor-kappa B (NF-κB) activation and excitotoxicity in rats striatal neurons.
Yan-Ru Wang, Shu Qin, Rong Han, Jun-Chao Wu, Zhong-Qin Liang, Zheng-Hong Qin, Yan Wang   +6 more
doaj   +1 more source

Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin [PDF]

, 2002
Schaschke N, Deluca D, Assfalg-Machleidt I, Hohneke C, Sommerhoff CP, Machleidt W. Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin.
Schaschke, Norbert, Assfalg-Machleidt, Irmgard, Schaschke, N., Deluca, D, Sommerhoff, C. P., Höhneke, C., Sommerhoff, CP, Machleidt, W., Assfalg-Machleidt, I, Machleidt, Werner, Deluca, D., Deluca, Dominga, Sommerhoff, Christian P., Assfalg-Machleidt, I., Hohneke, C, Höhneke, Clara, Machleidt, W   +16 more
core   +1 more source

Cloning of a cDNA encoding Schistosoma mansoni cathepsin C and expression in the yeast Pichia pastoris [PDF]

, 2003
The cDNA encoding the proenzyme of cathepsin C from the parasitic helminth Schistosoma mansoni was amplified from a cDNA library using 5’ and 3’ specific primers containing sites for SnaBI and Avrll digestion.
Carty, Charlene
core   +2 more sources