Results 181 to 190 of about 84,247 (372)
Lysosomal cathepsins and their regulation in aging and neurodegeneration
V. Stoka, V. Turk, B. Turk
semanticscholar +1 more source
PIEZO1 is highly correlated with mechanical stimulation, controlling bone growth and remodeling, while showing specific distribution characteristics under distinct loads. Upon dialectical review, this manuscript proposes that PIEZO1 could serve as a target for osteoporosis and a quantitative indicator for monitoring bone health in real‐time.
Chunyu Zhang, Yuehong Wang
wiley +1 more source
Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins [PDF]
Chigure Suzuki +7 more
openalex +1 more source
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan +10 more
wiley +1 more source
The causal relationship between cathepsins and ankylosing spondylitis: a two-sample Mendelian randomization study. [PDF]
Wu B +7 more
europepmc +1 more source
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source

