Results 81 to 90 of about 6,369 (264)

Metabolism of cathinone to (−)-norephedrine and (−)-norpseudoephedrine

Journal of Pharmacy and Pharmacology, 1986
Abstract S-(−)-Cathinone (S-(−)-α-aminopropiophenone) is the major active principle of khat leaves (Catha edulis), which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant. After oral administration of synthesized cathinone (isomers, racemate), 22–52% was recovered in 24 h urine samples mainly as ...
R, Brenneisen, S, Geisshüsler, X, Schorno   +2 more
openaire   +2 more sources

Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data. [PDF]

, 2018
New psychoactive substances (NPS) have increased in use and popularity worldwide. Wastewater analysis has been successfully applied to evaluate illicit drugs use within a population.
Bade, Richard, Bijlsma, Lubertus, Celma, Alberto, Gerber, Cobus, Hernandez, Felix, Painter, Ben, Stockham, Peter, White, Jason   +7 more
core   +1 more source

Repeated doses of methylone, a new drug of abuse, induce changes in serotonin and dopamine systems in the mouse [PDF]

, 2014
Rationale Methylone, a new drug of abuse sold as"bath salts' has similar effects to ecstasy or cocaine. Objective We have investigated changes in dopaminergic and serotoninergic markers, indicative of neuronal damage, induced by methylone in the frontal ...
Abad, Sonia, Camarasa García, Jordi, Escubedo Rafa, Elena, López Arnau, Raúl, Martínez-Clemente, José, Pubill Sánchez, David   +5 more
core   +2 more sources

Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature

Ecology and Evolution, Volume 16, Issue 4, April 2026.
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass, I. Flis, M. E. Hanley, M. E. Knight, S. M. Lane, G. Littlejohn, M. D. F. Thom, R. A. Billington, R. Boden, R. Cummins, B. J. Green, C. Griffin, S. Jones, D. Salmon, I. Sleep, N. Smirnoff, J. S. Ellis   +16 more
wiley   +1 more source

Development of a novel risk score reflecting the relative harm potential of synthetic cannabinoids based on prevalence estimates, well‐documented intoxication cases and basic pharmacological data

Addiction, Volume 121, Issue 4, Page 870-882, April 2026.
Abstract Background and aims While the health hazards of synthetic cannabinoid receptor agonists (SCRAs) are often approximated using in vitro pharmacological parameters as surrogate, this approach fails to consider pharmacokinetic and pharmacodynamic complexity.
Michaela J. Sommer, Katharina Elisabeth Grafinger, Maren Hermanns‐Clausen, Volker Auwärter   +3 more
wiley   +1 more source

Structure and Laboratory Diagnostics of Non-medical Consumption of Modern Synthetic Drugs

Неотложная медицинская помощь, 2019
The emergence of new synthetic narcotic drugs is noted all over the world. The situation causes significant difficulties for toxicologists, resuscitators, narcologists, and clinical laboratory diagnostics doctors due to the lack of available data on the ...
O. L. Balabanova, V. V. Shilov, A. N. Lodyagin, S. I. Glushkov   +3 more
doaj   +1 more source

Locomotor and discriminative stimulus effects of N-cyclohexyl butylone and N-cyclohexyl methylone

Frontiers in Pharmacology
BackgroundN-Cyclohexyl butylone and N-cyclohexyl methylone are cathinones found on the street that produce morbidity and mortality, but are not yet legally controlled, and there has been little or no pharmacological testing of these compounds.
Michael B. Gatch, Shuping Jia, Ritu A. Shetty, Rebecca D. Hill, Nathalie Sumien, Michael J. Forster   +5 more
doaj   +1 more source

Drug regulations and trafficking: Synthetic cannabinoids and cathinones in Hungary [PDF]

, 2023
József Haller, Éva Rompos, Írisz Szabó, Viktória Humli, László Christián   +4 more
openalex   +1 more source

Stimulant‐induced psychosis requires the same clinical priority as other psychotic disorders

Addiction, EarlyView.
Solja Niemelä
wiley   +1 more source

Suitability of Electrochemical Sensing on Screen‐Printed Carbon Electrodes for the Identification of Eutylone (βk‐EBDB)

Electroanalysis, Volume 38, Issue 3, March 2026.
Voltammetric methods on screen‐printed carbon electrodes were employed for the rapid detection of the synthetic cathinone β‐keto‐ethylbenzodioxolylbutanamine (βk‐EBDB) in supporting electrolyte and human biological fluids. The electroanalytical method is promising as a portable drug testing device for on‐site applications—providing a repeatable linear ...
Harry Van Dorssen, Shanlin Fu, Morgan Alonzo   +2 more
wiley   +1 more source