Results 51 to 60 of about 623,994 (347)
Frog Oocytes to Unveil the Structure and Supramolecular Organization of Human Transport Proteins
PLoS ONE, 2011 Structural analyses of heterologously expressed mammalian membrane proteins remain a great challenge given that microgram to milligram amounts of correctly folded and highly purified proteins are required.
M. Bergeron +7 more
semanticscholar +1 more source
Cation-Dependent Binding of Substrate to the Folate Transport Protein of Lactobacillus casei [PDF]
Journal of Bacteriology, 1982 Lactobacillus casei cells grown in the presence of limiting folate contained large amounts of a membrane-associated binding protein which mediates folate transport. Binding to this protein at 4°C was time and concentration dependent and at low levels (1 to 10 nM) of folate required 60 min to reach a steady state.
G B, Henderson, S, Potuznik
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Marine Drugs, 2017 This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto +6 more
doaj +1 more source
The FASEB Journal, 2015 The two drug transporters OATP1B3 and OCT1 are expressed at the basolateral membrane of human hepatocytes. In a search for potential interacting proteins a modified yeast‐two‐hybrid screen (DUALmembrane screen) identified OCT1 as an interaction partner for OATP1B3.
Jessica Shoop +3 more
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Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
, 2007 Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
core +1 more source
Frontiers in Plant Science, 2015 Ion transport is the fundamental factor determining salinity tolerance in plants. The Review starts from differences in ion transport between salt tolerant halophytes and salt-sensitive plants with an emphasis on transport of potassium and sodium via ...
Vadim eVolkov
doaj +1 more source
A human transporter protein that mediates the final excretion step for toxic organic cations [PDF]
Proceedings of the National Academy of Sciences, 2005 In mammals, toxic electrolytes of endogenous and exogenous origin are excreted through the urine and bile. Before excretion, these compounds cross numerous cellular membranes in a transporter-mediated manner. However, the protein transporters involved in the final excretion step are poorly understood.
Otsuka, Masato +5 more
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Frontiers in Cell and Developmental Biology, 2019 Ciliated cells exploit a specific transport system, the intraflagellar transport (IFT) system, to ensure the traffic of molecules from the cell body to the cilium.
Francesca Finetti +2 more
doaj +1 more source
Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability
Asian Journal of Pharmaceutical Sciences, 2020 Various drug transporters are widely expressed throughout the intestine and play important roles in absorbing nutrients and drugs, thus providing high quality targets for the design of prodrugs or nanoparticles to facilitate oral drug delivery.
Gang Wang +8 more
doaj +1 more source
Cation Effects on Protein Conformation and Transport in the Na+/Glucose Cotransporter
Journal of Biological Chemistry, 1997 Cation-driven cotransporters are essential membrane proteins in procaryotes and eucaryotes, which use the energy of the transmembrane electrochemical gradient to drive transport of a substrate against its concentration gradient. Do they share a common mechanism?
B A, Hirayama, D D, Loo, E M, Wright
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