Results 41 to 50 of about 623,994 (347)
Haematologica, 2009 Background Stomatocytoses are a group of inherited autosomal dominant hemolytic anemias and include overhydrated hereditary stomatocytosis, dehydrated hereditary stomatocytosis, hereditary cryohydrocytosis and familial pseudohyperkalemia.Design and ...
Achille Iolascon +10 more
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Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport
Journal of Cell Biology, 2017 The retromer complex, which recycles the cation-independent mannose 6-phosphate receptor (CI-MPR) from endosomes to the trans-Golgi network (TGN), is thought to consist of a cargo-selective VPS26–VPS29–VPS35 trimer and a membrane-deforming subunit of ...
Arunas Kvainickas +5 more
semanticscholar +1 more source
Substantia, 2018 Ca2+ and Cu2+ ATPases are enzyme proteins that utilize ATP for active transport of Ca2+ or Cu2+ across intracellular or cellular membranes.1-4 These enzymes are referred to as P-type ATPases since they utilize ATP through formation of a phosphorylated ...
Giuseppe Inesi
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Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. [PDF]
, 2018 Sodium-dependent glucose transporters (SGLTs) exploit sodium gradients to transport sugars across the plasma membrane. Due to their role in renal sugar reabsorption, SGLTs are targets for the treatment of type 2 diabetes.
Althoff, Thorsten +9 more
core +2 more sources
Journal of Biological Chemistry, 2005 Zinc is an essential component for the catalytic activity of numerous zinc-requiring enzymes. However, until recently little has been known about the molecules involved in the pathways required for supplying zinc to these enzymes.
Tomoyuki Suzuki +6 more
semanticscholar +1 more source
An extracellular cation coordination site influences ion conduction of OsHKT2;2
BMC Plant Biology, 2019 Background HKT channels mediate sodium uniport or sodium and potassium symport in plants. Monocotyledons express a higher number of HKT proteins than dicotyledons, and it is only within this clade of HKT channels that cation symport mechanisms are found.
Janin Riedelsberger +4 more
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Frontiers in Plant Science, 2023 The zinc/iron-regulated transporter-like protein (ZIP) gene family first identified in plants is highly distributed in the plant kingdom. This family has previously been reported to transport several essential and non-essential cationic elements ...
Daniel Dastan Rezabala Pacheco +3 more
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Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children [PDF]
Drug Metabolism and Disposition, 2017 Organic cation transporter 1 (OCT1) plays an important role in the disposition of clinically important drugs, and the capacity of OCT1 activity is presumed to be proportional to the protein expression level in organ tissues. Knowledge of OCT1 protein expression in children, especially neonates and small infants, is currently very limited.
David, Hahn +3 more
openaire +2 more sources
PLoS ONE, 2013 BackgroundMembrane proteins play a key role in many fundamental cellular processes such as transport of nutrients, sensing of environmental signals and energy transduction, and account for over 50% of all known drug targets.
Pikyee Ma +12 more
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The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes
Cell Reports, 2017 Proper intracellular cholesterol trafficking is critical for cellular function. Two lysosome-resident proteins, NPC1 and NPC2, mediate the egress of low-density lipoprotein-derived cholesterol from lysosomes.
Jian Wei +10 more
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