Results 21 to 30 of about 623,994 (347)

Kidney‐specific expression of a novel mouse organic cation transporter‐like protein [PDF]

FEBS Letters, 1997
Using the signal sequence trap method, we have cloned a novel 12‐membrane‐spanning transporter‐like protein, termed renal‐specific transporter (RST), from the mouse kidney. RST is a 553‐amino‐acid protein highly homologous to recently cloned organic cation transporters, e.g.
Mori, Kiyoshi, Ogawa, Yoshihiro, Ebihara, Ken, Aoki, Tomohiro, Tamura, Naohisa, Sugawara, Akira, Kuwahara, Takashi, Ozaki, Shoichi, Mukoyama, Masashi, Tashiro, Kei, Tanaka, Issei, Nakao, Kazuwa   +11 more
openaire   +2 more sources

Genome-wide analysis of the apple CaCA superfamily reveals that MdCAX proteins are involved in the abiotic stress response as calcium transporters

BMC Plant Biology, 2021
Background Calcium (Ca2+) plays an important role in plant growth and development, and the maintenance of calcium homeostasis is necessary for the survival of all plant species. Ca2+/H+ exchangers (CAXs) are a subgroup of the CaCA (Ca2+/cation antiporter)
Ke Mao, Jie Yang, Min Wang, Huayu Liu, Xin Guo, Shuang Zhao, Qinglong Dong, Fengwang Ma   +7 more
doaj   +1 more source

Rescue of Misfolded Organic Cation Transporter 3 Variants

Cells, 2022
Organic cation transporters (OCTs) are membrane proteins that take up monoamines, cationic drugs and xenobiotics. We previously reported novel missense mutations of organic cation transporter 3 (OCT3, SLC22A3), some with drastically impacted transport ...
Thomas J. F. Angenoorth, Julian Maier, Stevan Stankovic, Shreyas Bhat, Sonja Sucic, Michael Freissmuth, Harald H. Sitte, Jae-Won Yang   +7 more
doaj   +1 more source

Structure of cytosine transport protein CodB provides insight into nucleobase‐cation symporter 1 mechanism [PDF]

The EMBO Journal, 2022
AbstractCodB is a cytosine transporter from the Nucleobase‐Cation‐Symport‐1 (NCS1) transporter family, a member of the widespread LeuT superfamily. Previous experiments with the nosocomial pathogen Pseudomonas aeruginosa have shown CodB as also important for the uptake of 5‐fluorocytosine, which has been suggested as a novel drug to combat ...
Caitlin E Hatton, Deborah H Brotherton, Mahalah Spencer, Alexander D Cameron   +3 more
openaire   +2 more sources

Cation permeability in CorA family of proteins

Scientific Reports, 2020
CorA proteins belong to 2-TM-GxN family of membrane proteins, and play a major role in Mg2+ transport in prokaryotes and eukaryotic mitochondria. The selection of substrate is believed to occur via the signature motif GxN, however there is no consensus ...
Artem Stetsenko, Albert Guskov
doaj   +1 more source

A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models [PDF]

, 2020
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic homeostasis of this essential trace element. This review summarizes the key aspects of human zinc homeostasis and distribution.
Haase, Hajo, Maares, Maria
core   +1 more source

Genome-Wide Identification of Strawberry Metal Tolerance Proteins and Their Expression under Cadmium Toxicity

Horticulturae, 2022
Metal tolerance proteins (MTPs) are divalent cation transporters, known to upkeep the mineral nutrition of plants and heavy metal transport at cell, tissue, or whole plant levels.
Muhammad Salman Haider, Taha Majid Mahmood Sheikh, Songtao Jiu, Muqaddas Aleem, Waqar Shafqat, Komal Shoukat, Nadeem Khan, Muhammad Jafar Jaskani, Summar A. Naqvi, Sezai Ercisli, Amine Assouguem, Mohammed Kara, Riaz Ullah, Maha Aljabri, Sameer H. Qari   +14 more
doaj   +1 more source

Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor. [PDF]

, 2017
About 50% of the world's arable land is strongly acidic (pH ≤ 5). The low pH solubilizes root-toxic ionic aluminium (Al3+) species from clay minerals, driving the evolution of counteractive adaptations in cultivated crops.
Chang, Geoffrey, Doshi, Rupak, Garza, Denisse M, Kochian, Leon V, McGrath, Aaron P, Piñeros, Miguel, Szewczyk, Paul   +6 more
core   +3 more sources

Identification and Characterization of Dmct: A Cation Transporter in Yarrowia lipolytica Involved in Metal Tolerance

Journal of Fungi, 2023
Yarrowia lipolytica is a dimorphic fungus used as a model organism to investigate diverse biotechnological and biological processes, such as cell differentiation, heterologous protein production, and bioremediation strategies.
Katia Jamileth González-Lozano, Elva Teresa Aréchiga-Carvajal, Zacarías Jiménez-Salas, Debany Marlen Valdez-Rodríguez, Claudia Geraldine León-Ramírez, José Ruiz-Herrera, Juan Manuel Adame-Rodríguez, Manuel López-Cabanillas-Lomelí, Eduardo Campos-Góngora   +8 more
doaj   +1 more source

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn, Alexandersson, Armengaud, Banuelos, Benschop, Brugiere, Carter, Chrispeels, Ducos, Dunkley, Endler, Gaxiola, Gierth, Jacquinod, Komatsu, Larsson, Loque, Lüttge, Ma, Maathuis, Maathuis, Marmagne, Morsomme, Niittyla, Nühse, Nühse, Paszkowski, Peltier, Pighin, Rentsch, Sancenon, Tanaka, Tornroth-Horsefield, Toyofuku, Vitart, Whiteman, Wintz, Wu, Yazaki   +38 more
core   +1 more source