Cation and sugar selectivity determinants in a novel family of transport proteins [PDF]
Molecular Microbiology, 1996 A new family of homologous membrane proteins that transport galactosides–pentoses–hexuronides (GPH) is described. By analysing the aligned amino acid sequences of the GPH family, and by exploiting their different specificities for cations and sugars, we have designed mutations that yield novel insights into the nature of ligand binding sites in ...
B. Poolman +7 more
semanticscholar +6 more sources
Physiological and Putative Organic Cation Transporter Expression Response to Alizarin Dye Exposure in Aedes aegypti Mosquitoes [PDF]
InsectsThere remains an urgent need for knowledge regarding the molecular and genetic mechanisms in Aedes aegypti to support the fight against mosquito-borne illness, one of these areas being xenobiotic transport.
Naomi R. Kennel, Matthew F. Rouhier
doaj +2 more sources
Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters
Frontiers in Plant Science, 2020 The processes of plant nutrition, stress tolerance, plant growth, and development are strongly dependent on transport of mineral nutrients across cellular membranes. Plant membrane transporters are key components of these processes.
Stanislav V. Isayenkov +5 more
doaj +2 more sources
Dietary supplementation of essential oils in dairy cows: evidence for stimulatory effects on nutrient absorption [PDF]
Animal, 2019 Results of recent in vitro experiments suggest that essential oils (EO) may not only influence ruminal fermentation but also modulate the absorption of cations like Na+, Ca2+ and NH4+ across ruminal epithelia of cattle and sheep through direct ...
H.-S. Braun +4 more
doaj +3 more sources
Structural and functional mapping of ion access pathways in the human K+-dependent Na+/Ca2+ exchanger NCKX2 using cysteine scanning mutagenesis, thiol-modifying reagents, and homology modelling [PDF]
ChannelsK+-dependent Na+/Ca2+ exchanger proteins (NCKX) are members of the CaCA superfamily with critical roles in vision, skin pigmentation, enamel formation, and neuronal functions.
Robert T. Szerencsei +5 more
doaj +2 more sources
The molecular mechanism of fluoride export by the eukaryotic fluoride channel FEX [PDF]
Nature CommunicationsMuch of life on Earth, including plants, fungi, and bacteria, evolved to resist toxic environmental fluoride. In eukaryotes, the major resistance mechanism is fluoride export by membrane proteins known as FEX. Using electrophysiology and transport assays,
Chia-Yu Kang +5 more
doaj +2 more sources
Light-Modulated Cationic and Anionic Transport Across Protein Biopolymers [PDF]
Angewandte Chemie International Edition, 2021 Light is a convenient source of energy and the heart of light-harvesting natural systems and devices. Here, we show light-modulation of both the chemical nature and ionic charge carrier concentration within a protein-based biopolymer that was covalently functionalized with photoacids or photobases.
Alex Burnstine‐Townley +4 more
openaire +2 more sources
In vitro Assay to Evaluate Cation Transport of Ionophores
Bio-Protocol, 2022 Ion homeostasis is a fundamental regulator of cellular processes and depends upon lipid membranes, which function as ion permeability barriers. Ionophores facilitate ion transport across cell membranes and offer a way to manipulate cellular ion ...
Huriye Huriye D. Uzun +3 more
doaj +1 more source
Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. [PDF]
PLoS ONE, 2018 Our laboratory has developed bioinformatic strategies for identifying distant phylogenetic relationships and characterizing families and superfamilies of transport proteins.
Arturo Medrano-Soto +5 more
doaj +1 more source
Elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions [PDF]
, 2013 Peer reviewedPublisher ...
Akmakjian, Garo +12 more
core +14 more sources