Results 61 to 70 of about 2,178,073 (385)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

The detection of capsaicin and dihydrocapsaicin in horse serum following long-term local administration

BMC Veterinary Research, 2018
Background Capsaicin and dihydrocapsaicin are alkaloids with analgesic effects in humans and animals. When used locally, both of them minimalise pain sensation by defunctionalising nerve endings.
A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, P. Szpot, M. Zawadzki, A. Niedzwiedz   +6 more
doaj   +1 more source

Who is the Weakest Link? A Network Vulnerability Analysis Using a Congested Transport Assignment

Findings, 2022
We propose a user-equilibrium congested transit assignment model for a full-scan network vulnerability analysis by relying on the computations of network science indicators for infrastructure and service graphs.
Oded Cats, Sanmay Shelat
doaj   +1 more source

The civic engagement community participation thriving model: A multi-faceted thriving model to promote socially excluded young adult women

Frontiers in Psychology, 2022
Social policies to promote socially excluded young adult women generally concentrate on education, employment, and residence but tend to neglect thriving. The current article puts forward a Civic Engagement Community Participation Thriving Model (CECP-TM)
Irit Birger Sagiv, Limor Goldner, Yifat Carmel, Yifat Carmel   +3 more
doaj   +1 more source

Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma. [PDF]

, 2019
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL).
Ackermann, Mark R, Chow, Betty, Estep, J Scot, Hill, Steve L, Lidbury, Jonathan A, Marsilio, Sina, Pilla, Rachel, Sarawichitr, Benjamin, Steiner, Joerg M, Suchodolski, Jan S   +9 more
core   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Microbiota alterations in acute and chronic gastrointestinal inflammation of cats and dogs.

World Journal of Gastroenterology, 2014
The intestinal microbiota is the collection of the living microorganisms (bacteria, fungi, protozoa, and viruses) inhabiting the gastrointestinal tract. Novel bacterial identification approaches have revealed that the gastrointestinal microbiota of dogs ...
Julia B Honneffer, Y. Minamoto, J. Suchodolski   +2 more
semanticscholar   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Ecological modeling, biogeography, and phenotypic analyses setting the tiger cats’ hyperdimensional niches reveal a new species

Scientific Reports
Recently, the tiger-cat species complex was split into Leopardus tigrinus and Leopardus guttulus, along with other proposed schemes. We performed a detailed analysis integrating ecological modeling, biogeography, and phenotype of the four originally ...
Tadeu G. de Oliveira, Lester A. Fox-Rosales, José D. Ramírez-Fernández, Juan C. Cepeda-Duque, Rebecca Zug, Catalina Sanchez-Lalinde, Marcelo J. R. Oliveira, Paulo H. D. Marinho, Alejandra Bonilla-Sánchez, Mara C. Marques, Katia Cassaro, Ricardo Moreno, Damián Rumiz, Felipe B. Peters, Josué Ortega, Gitana Cavalcanti, Michael S. Mooring, Steven R. Blankenship, Esteban Brenes-Mora, Douglas Dias, Fábio D. Mazim, Eduardo Eizirik, Jaime L. Diehl, Rosane V. Marques, Ana Carolina C. Ribeiro, Reginaldo A. Cruz, Emanuelle Pasa, Lyse P. C. Meira, Alex Pereira, Guilherme B. Ferreira, Fernando F. de Pinho, Liana M. M. Sena, Vinícius R. de Morais, Micheli Ribeiro Luiz, Vitor E. C. Moura, Marina O. Favarini, Karla P. G. Leal, Paulo G. C. Wagner, Maurício C. dos Santos, James Sanderson, Elienê P. Araújo, Flávio H. G. Rodrigues   +41 more
doaj   +1 more source

The Girl in the Spotlight: Vermeer at work, his materials and techniques in Girl with a Pearl Earring

Heritage Science, 2020
The 2018 technical examination project The Girl in the Spotlight aimed to characterise the materials and techniques that Johannes Vermeer used to paint Girl with a Pearl Earring (c. 1665, Mauritshuis).
Abbie Vandivere, Jørgen Wadum, Emilien Leonhardt   +2 more
doaj   +1 more source