Results 221 to 230 of about 2,942 (237)
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Activating CatSper

Science Signaling, 2011
Progesterone stimulates calcium influx in human sperm through the CatSper channel.
openaire   +1 more source

CatSper in Male Infertility

2013
In 2001, two groups independently reported different components of a novel Ca2+ channel named CatSper, which is expressed only in the testis and localized in the sperm flagellum. Now, we know that CatSper is a sperm-specific Ca2+ channel composed of four distinct pore-forming subunits accompanied with, at least, three auxiliary subunits. Although there
Takuya Nishigaki   +2 more
openaire   +1 more source

A bioinformatics analysis of the CatSper channel in the class Actinopterygii

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2022
The regulation of sperm motility is controlled by several variables, including mainly ion concentrations. In fish, Ca2+ concentrations play an important role in the regulation of sperm motility, and several reports highlight the importance of certain Ca2+ channels in the regulation of this cell function. CatSper is a calcium channel scarcely studied in
Jorge F, Beltrán   +7 more
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[CatSper and sperm hyperactivation].

Zhonghua nan ke xue = National journal of andrology, 2007
Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are putative cation channels expressed exclusively in the membranes of the sperm flagellum.
Li-juan, Kong   +2 more
openaire   +1 more source

Insights into sperm cell motility signaling through sNHE and the CatSpers

Molecular and Cellular Endocrinology, 2006
Successful natural reproduction normally requires vigorously motile spermatozoa. Using a signal peptide trapping strategy, we identified two new genes, a putative sperm Na+/H+ exchanger (sNHE) and the putative cation channel CatSper2, with unique and essential roles in sperm motility.
Timothy A, Quill   +2 more
openaire   +2 more sources

A Model of CatSper Channel Mediated Calcium Dynamics in Mammalian Spermatozoa

Bulletin of Mathematical Biology, 2010
CatSpers are calcium (Ca(2+)) channels that are located along the principal piece of mammalian sperm flagella and are directly linked to sperm motility and hyperactivation. It has been observed that Ca(2+) entry through CatSper channels triggers a tail to head Ca(2+) propagation in mouse sperm, as well as a sustained increase of Ca(2+) in the head ...
Olson, Sarah D.   +2 more
openaire   +3 more sources

Progesterone and CatSper dependency

International Journal of Andrology, 2012
Martin, Blomberg Jensen   +1 more
openaire   +2 more sources

A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking

Proceedings of the National Academy of Sciences of the United States of America, 2023
Xiaofang Huang   +2 more
exaly  

The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm

Nature, 2011
Timo Strünker   +2 more
exaly  

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