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Science Signaling, 2011
Progesterone stimulates calcium influx in human sperm through the CatSper channel.
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Progesterone stimulates calcium influx in human sperm through the CatSper channel.
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2013
In 2001, two groups independently reported different components of a novel Ca2+ channel named CatSper, which is expressed only in the testis and localized in the sperm flagellum. Now, we know that CatSper is a sperm-specific Ca2+ channel composed of four distinct pore-forming subunits accompanied with, at least, three auxiliary subunits. Although there
Takuya Nishigaki +2 more
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In 2001, two groups independently reported different components of a novel Ca2+ channel named CatSper, which is expressed only in the testis and localized in the sperm flagellum. Now, we know that CatSper is a sperm-specific Ca2+ channel composed of four distinct pore-forming subunits accompanied with, at least, three auxiliary subunits. Although there
Takuya Nishigaki +2 more
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A bioinformatics analysis of the CatSper channel in the class Actinopterygii
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2022The regulation of sperm motility is controlled by several variables, including mainly ion concentrations. In fish, Ca2+ concentrations play an important role in the regulation of sperm motility, and several reports highlight the importance of certain Ca2+ channels in the regulation of this cell function. CatSper is a calcium channel scarcely studied in
Jorge F, Beltrán +7 more
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[CatSper and sperm hyperactivation].
Zhonghua nan ke xue = National journal of andrology, 2007Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are putative cation channels expressed exclusively in the membranes of the sperm flagellum.
Li-juan, Kong +2 more
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Insights into sperm cell motility signaling through sNHE and the CatSpers
Molecular and Cellular Endocrinology, 2006Successful natural reproduction normally requires vigorously motile spermatozoa. Using a signal peptide trapping strategy, we identified two new genes, a putative sperm Na+/H+ exchanger (sNHE) and the putative cation channel CatSper2, with unique and essential roles in sperm motility.
Timothy A, Quill +2 more
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A Model of CatSper Channel Mediated Calcium Dynamics in Mammalian Spermatozoa
Bulletin of Mathematical Biology, 2010CatSpers are calcium (Ca(2+)) channels that are located along the principal piece of mammalian sperm flagella and are directly linked to sperm motility and hyperactivation. It has been observed that Ca(2+) entry through CatSper channels triggers a tail to head Ca(2+) propagation in mouse sperm, as well as a sustained increase of Ca(2+) in the head ...
Olson, Sarah D. +2 more
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Progesterone and CatSper dependency
International Journal of Andrology, 2012Martin, Blomberg Jensen +1 more
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Proceedings of the National Academy of Sciences of the United States of America, 2023
Xiaofang Huang +2 more
exaly
Xiaofang Huang +2 more
exaly
The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm
Nature, 2011Timo Strünker +2 more
exaly

