Results 101 to 110 of about 3,950,087 (325)

Comparison of Analgesic Efficacy of Caudal Block and Ultrasound Guided TAP Block In Pediatric Patients Undergoing Lower Abdominal Surgeries [PDF]

, 2021
Background: Caudal block is the most frequently used regional anesthetic for pediatric analgesia, technique with the disadvantage of limited duration of action associated with an undesired motor blockade and other complications. Recently, the transversus
Mohammad Khairat, Usma Jabeen, Zaka Sameen   +2 more
core   +1 more source

Dexmedetomidine with magnesium sulphate as adjuvants in caudal block to augment anaesthesia and analgesia in paediatric lower abdominal surgeries

Egyptian Journal of Anaesthesia, 2018
Purpose To investigate the implication of dexmedetomidine and magnesium sulphate addition to bupivacaine in caudal anesthesia in paediatric lower abdominal surgeries. Study design Randomized controlled trial.
J. Sayed, E. Kamel, M. Riad, S. Abd-Elshafy, R. Hanna   +4 more
semanticscholar   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Comparative study between the analgesic effects of transversus abdominis plane block and caudal block in lower abdominal surgeries in pediatrics compared with general anesthesia

Al-Azhar Assiut Medical Journal, 2018
Background Pain experienced after abdominal surgery is derived from abdominal wall incision. Transversus abdominis plane (TAP) block is a novel approach for blocking abdominal wall neural afferents.
Ismail F Ezz, Said M Alaa, Abd El-Aziz F Ahmed, Ali A Kareem   +3 more
doaj   +1 more source

Comparison of the Success Rates and Haemodynamic Changes of Caudal Block .and Dorsal Penile Nerve Block in Paediatric Day-Case Circumcision

, 2017
Background: Regional anaesthetic techniques such as caudal block and dorsal penile nerve block arc safe and provide very effective postoperative pain relief for circumcision.
Tanimu, Samboy, Shehu, Panda U., Tela, Mohammed, Saniadamu, Samuelwabada, Adamu, Abubakar S.   +4 more
core   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

A comparison of the efficacy of penile block and caudal block with bupivacaine on perioperative bleeding in circumcised children

Medicine Science
The management of postoperative pain is a fundamental aspect of surgical care. To achieve the aforementioned result, a variety of blocks may be utilized.
Ayse Betul Ozturk, Ibrahim Kosemen
doaj   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

Our Experiences with Caudal Epidural and Transversus Abdominis Plan (tap) Block in Pediatric Patiens

, 2023
Our Experiences with Caudal Epidural and Transversus Abdominis Plan (tap)Block in Pediatric PatiensYeşim ANDIRAN ŞENAYLI1, Cevdet YARDIMCI1, Muhammed Nuri POLAT1, Sevgi ULUSOY TANGÜL21Bozok Üniversitesi Anesteziyoloji ve Reanimasyon  ...
YARDIMCI, CEVDET, ANDIRAN ŞENAYLI, YEŞİM, ULUSOY TANGÜL, SEVGİ, POLAT, MUHAMMED NURİ   +3 more
core  

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source