Results 31 to 40 of about 9,491,507 (312)

Assessing the association between age at first sexual intercourse and migraine: a Mendelian randomization study

Frontiers in Neurology
Background and objectivesAs indicated by observational and genetic variation studies, age at first sexual intercourse (AFS) may be associated with migraine attack, but there is a lack of evidence from real-world studies due to ethical concerns. Therefore,
Guoliang Zhu, Guoliang Zhu, Miao Wang, Yawen Wang, Yawen Wang, Fanyi Kong   +5 more
doaj   +1 more source

Exploring the mediating role of blood metabolites in the relationship between gut microbiota and gastric cancer risk: a Mendelian randomization study

Frontiers in Cellular and Infection Microbiology
BackgroundPrior studies have established correlations between gut microbiota (GM) dysbiosis, circulating metabolite alterations, and gastric cancer (GC) risk.
Xiaocheng Li, Xiaocheng Li, Huapeng Lin, Huapeng Lin, Huapeng Lin, Jing Peng, Jianping Gong   +6 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

The causal relationship between type 2 diabetes mellitus and isolated REM sleep behavior disorder: results from multivariable and network Mendelian randomization analysis

Frontiers in Endocrinology
ObjectivesTo investigate the causal relationship between type 2 diabetes mellitus (T2DM, exposure) and isolated REM sleep behavior disorder (iRBD, outcome).MethodsGenome-wide association study (GWAS) data for iRBD comprised 9,447 samples, including 1,061
Ru-Yu Zhang, Ru-Yu Zhang, Jin-Yu Li, Yu-Ning Liu, Zi-Xuan Zhang, Jie Zhao, Fu-Jia Li, Fu-Jia Li   +7 more
doaj   +1 more source

Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study

BMC Medicine, 2023
Background Stroke is a major cause of mortality and long-term disability worldwide. Whether the associations between brain imaging-derived phenotypes (IDPs) and stroke are causal is uncertain.
Ke Yu, Xiao-Feng Chen, Jing Guo, Sen Wang, Xiao-Ting Huang, Yan Guo, Shan-Shan Dong, Tie-Lin Yang   +7 more
doaj   +1 more source

Causality and Association: The Statistical and Legal Approaches

Statistical Science, 2007
This paper discusses different needs and approaches to establishing ``causation'' that are relevant in legal cases involving statistical input based on epidemiological (or more generally observational or population-based) information. We distinguish between three versions of ``cause'': the first involves negligence in providing or allowing exposure ...
Mengersen, Kerrie, Moynihan, Sean, Tweedie, Richard   +2 more
openaire   +4 more sources

The role of causal inference in health services research II: a framework for causal inference. [PDF]

, 2020
In a previous Hints and Kinks, we discussed the role of causal inference in tasks of health services research (HSR) using examples from health system interventions (Moser et al. 2020).
Zwahlen, Marcel, Puhan, Milo A, Moser, André, Puhan, Milo A; https://orcid.org/, Moser A, Puhan MA, Zwahlen M   +6 more
core   +2 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

The relationship between major depression and migraine: A bidirectional two-sample Mendelian randomization study

Frontiers in Neurology, 2023
BackgroundPrevious epidemiological and other studies have shown an association between major depressive disorder (MDD) and migraine. However, the causal relationship between them remains unclear.
Xiaofeng Lv, Xiaofeng Lv, Bojun Xu, Xiurong Tang, Shanshan Liu, Jun-Hui Qian, Jun-Hui Qian, Julan Guo, Jian Luo   +8 more
doaj   +1 more source

Causal webs in epidemiology [PDF]

, 2009
The notion of ‘causal web’ emerged in the epidemiological literature in the early Sixties and had to wait until the Nineties for a thorough critical appraisal. Famously, Nancy Krieger argued that such a notion isn’t helpful unless we specify what kind of
Russo, Federica, Federica Russo
core