Results 41 to 50 of about 9,491,507 (312)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Genetic liability to mental disorders in relation to the risk of hypertension

Frontiers in Cardiovascular Medicine, 2023
BackgroundObservational studies have indicated that psychosocial factors contribute to hypertension; however, the causality of these associations remains unclear due to reverse causality and confounders. We aim to assess the causal associations of mental
Ning Huangfu, Ning Huangfu, Ning Huangfu, Yunlong Lu, Hongchuang Ma, Hongchuang Ma, Ziwei Hu, Ziwei Hu, Hanbin Cui, Hanbin Cui, Hanbin Cui, Fangkun Yang, Fangkun Yang, Fangkun Yang   +13 more
doaj   +1 more source

RFCT: An Association-Based Causality Miner [PDF]

, 2002
Discovering causal relations in a system is essential to understanding how it works and to learning how to control the behaviour of the system. RFCT is a causality miner that uses association relations as the basis for the discovery of causal relations. It does so by making explicit the temporal relationships among the data.
Kamran Karimi, Howard J. Hamilton
openaire   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Causal relationship between mitochondrial-associated proteins and cerebral aneurysms: a Mendelian randomization study

Frontiers in Neurology
BackgroundCerebral aneurysm is a high-risk cerebrovascular disease with a poor prognosis, potentially linked to multiple factors. This study aims to explore the association between mitochondrial-associated proteins and the risk of cerebral aneurysms ...
Shuai Wang, Jiajun Wang, Zihui Niu, Kang Zhang, Tao Yang, Shiqiang Hou, Ning Lin   +6 more
doaj   +1 more source

MR estimates of the causal association between HF and Kidney Function and CKD(after MR-presso).

, 2023
MR estimates of the causal association between HF and Kidney Function and CKD(after MR-presso).
Junyu Zhang (290066), Zhixi Hu (12324028), Jiahao Ye (13230823), Yuquan Tan (17616043)   +3 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Beyond Covariation: Cues to Causal Structure [PDF]

, 2010
Causal induction has two components: learning about the structure of causal models and learning about causal strength and other quantitative parameters. This chapter argues for several interconnected theses.
Hagmaye, Y, Lagnado, DA, Sloman, SA, Waldmann, MR   +3 more
core  

The structure of causal sets [PDF]

, 2011
More often than not, recently popular structuralist interpretations of physical theories leave the central concept of a structure insufficiently precisified.
Christian Wüthrich, Wuthrich, Christian
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source