Results 51 to 60 of about 9,491,507 (312)

The role of mitochondrial DNA copy number in autoimmune disease: a bidirectional two sample mendelian randomization study

Frontiers in Immunology
BackgroundMitochondrial DNA (mtDNA) plays an important role in autoimmune diseases (AD), yet the relationship between mitochondria and autoimmune disease is controversial.
Zhekang Liu, Qingan Fu, Yijia Shao, Xinwang Duan   +3 more
doaj   +1 more source

Joint Analysis of Genetic Correlation, Mendelian Randomization and Colocalization Highlights the Bi-Directional Causal Association Between Hypothyroidism and Primary Biliary Cirrhosis

Frontiers in Genetics, 2021
Background: Hypothyroidism and primary biliary cirrhosis (PBC) are often co-existed in observational epidemiological studies. However, the causal relationship between them remains unclear.Methods: Genetic correlation, Mendelian randomization (MR) and ...
Yanjun Wang, Ping Guo, Yanan Zhang, Lu Liu, Ran Yan, Zhongshang Yuan, Yongfeng Song, Yongfeng Song, Yongfeng Song   +8 more
doaj   +1 more source

EPR, Robustness and the Causal Markov Condition [PDF]

, 2007
It is still a matter of controversy whether the Principle of the Common Cause (PCC) can be used as a basis for sound causal inference. It is thus to be expected that its application to quantum mechanics should be a correspondingly controversial issue ...
San Pedro, Iñaki, Suárez, Mauricio
core  

Vision as causal activation and association

, 1985
Vision is interpreted as embedding an image in a causal framework. Specifically, vision is decomposed into image recognition and image understanding. A fuzzy cognitive map (FCM)__a fuzzy causal graph--is selected as the causal framework in which vision ...
Bart Kosko, John S. Limm, John S. Limn
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Potential causal association of diabetes mellitus and blood glucose related indexes with the onset of epilepsy: a two-sample Mendelian randomization study

Frontiers in Neurology
AimDiabetes mellitus (DM) may promote the occurrence of epilepsy through mechanisms, such as inflammation, immune imbalance, and cerebrovascular injury, caused by metabolic abnormalities.
Mengting Zhu, Shuying Ling
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Genetically predicted tea intake increases the risk of osteoarthritis: A Mendelian randomization study

Frontiers in Genetics, 2022
Background: This study aimed to clarify the relationship between tea consumption and osteoarthritis (OA).Methods: Common single-nucleotide polymorphisms (SNPs) from the Open Genome-wide Association Studies database were obtained. Summary statistics on OA
Gang Li, Zhe Zhang, Yang Liu
doaj   +1 more source

Probabilistic Reasoning Across the Causal Hierarchy

, 2020
We propose a formalization of the three-tier causal hierarchy of association, intervention, and counterfactuals as a series of probabilistic logical languages.
Icard, Thomas, Ibeling, Duligur
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source