Results 111 to 120 of about 16,076,570 (308)

Michotte’s research on perceptual impressions of causality: a registered replication study

Royal Society Open Science
Michotte (Michotte A, 1946 La perception de la causalité. Louvain: Études de Psychologie. Michotte A, 1954 La perception de la causalité, 2nd éd. Louvain: Études de Psychologie. Michotte A, 1963 The perception of causality. (Transl. by TR Miles, E Miles).
Peter White
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Causal diffusions, causal Zeno effect and collision number

, 2009
We consider diffusion processes with the help of Markov random walk models. Especially the process of diffusion of a relativistic particle in a relativistic equilibrium system is considered. We interpret one of the results as causal Zeno effect for its similarity to quantum Zeno effect. Another problem we considered is about collision number. Basing on
Ren, Ji-Rong, Li, Ming-fan, Zhu, Tao
openaire   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Causal relationships between gut microbiome and obstructive sleep apnea: a bi-directional Mendelian randomization

Frontiers in Microbiology
BackgroundPrevious studies have identified a clinical association between gut microbiota and Obstructive sleep apnea (OSA), but the potential causal relationship between the two has not been determined.
Liangfeng Liu, Guanwen He, Rong Yu, Bingbang Lin, Liangqing Lin, Rifu Wei, Zhongshou Zhu, Yangbin Xu, Yangbin Xu   +8 more
doaj   +1 more source

Dynamic Causal Structure Discovery and Causal Effect Estimation

Proceedings of the 31st ACM SIGKDD Conference on Knowledge Discovery and Data Mining V.1
To represent the causal relationships between variables, a directed acyclic graph (DAG) is widely utilized in many areas, such as social sciences, epidemics, and genetics. Many causal structure learning approaches are developed to learn the hidden causal structure utilizing deep-learning approaches.
Jianian Wang, Rui Song
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Causal effects and metabolites mediators between immune cell and risk of breast cancer: a Mendelian randomization study

Frontiers in Genetics
Introduction: The incidence and mortality of female breast cancer remain high, and the immune microenvironment of breast cancer has undergone significant alterations.
Ruijie Ming, Huan Wu, Hong Liu, Fangbiao Zhan, Xingan Qiu, Ming Ji   +5 more
doaj   +1 more source

Effects of Causal Determinism on Causal Learning Trajectories [PDF]

, 2020
Research on causal learning suggests that people are capable of learning nondeterministic causal relations, but might expectcausal relations to be deterministic in certain contexts. In two experiments, we demonstrated that peoples expectations ofcausal determinism are context-sensitive and can influence causal judgments in a sequential learning task ...
Dinh, Phuong (Phoebe), Danks, David
openaire  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source