Results 81 to 90 of about 16,076,570 (308)
It's not unreasonable to think that in-game sporting performance can be affected partly by what takes place off the court. We can't observe what happens between games directly. Instead, we proxy for the possibility of athletes partying by looking at play following games in party cities. We are interested to see if teams exhibit a decline in performance
Santucci, Andreas, Lax, Eric
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionThe oral cavity and gut tract, being interconnected and rich in microbiota, may have a shared influence on gingivitis. However, the specific role of distinct gut microbiota taxa in gingivitis remains unexplored.
Zhou Hang, Chen Rouyi, Li Sen
doaj +1 more source
How contrast situations affect the assignment of causality in symmetric physical settings
Frontiers in Psychology, 2015 In determining the prime cause of a physical event, people often weight one of two entities in a symmetric physical relation as more important for bringing about the causal effect than the other. In a broad survey (Bender and Beller, 2011), we documented
Sieghard eBeller, Andrea eBender
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Association of coffee intake with bone mineral density: a Mendelian randomization study
Frontiers in EndocrinologyBackgroundIn observational studies, the relationship between coffee intake and bone mineral density (BMD) is contradictory. However, residual confounding tends to bias the results of these studies. Therefore, we used a two-sample Mendelian randomization (
Yang Ye +6 more
doaj +1 more source
Information Theoretic Causal Effect Quantification
Entropy, 2019 Modelling causal relationships has become popular across various disciplines. Most common frameworks for causality are the Pearlian causal directed acyclic graphs (DAGs) and the Neyman-Rubin potential outcome framework.
Aleksander Wieczorek, Volker Roth
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Estimating cross‐population genetic correlations of causal effect sizes
Genetic Epidemiology, 2018 Recent studies have examined the genetic correlations of single‐nucleotide polymorphism (SNP) effect sizes across pairs of populations to better understand the genetic architectures of complex traits.
K. Galinsky +7 more
semanticscholar +1 more source