Results 121 to 130 of about 33,357 (216)

Non‐Contact Transspatial Regulatory Function of the Extracellular Matrix

Smart Medicine, Volume 5, Issue 4, August 2026.
Non‐contact transspatial regulation of the extracellular matrix (ECM), whereby the ECM remotely modulates cellular behavior without direct physical contact, is proposed and systematically investigated for the first time. This process involves multiple pathways and components, with actin‐dependent macropinocytosis playing a predominant role potentially.
Ting Cao, Chen Yang, Zhengyang Wang, Changmin Shao, Ziye Xu, Baode Chen, Jiayu Zhang, Yongcheng Wang, Fangfu Ye   +8 more
wiley   +1 more source

Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy

Small Science, Volume 6, Issue 8, August 2026.
Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik, Urooj Yousaf Virk, Mohamed Salah Attia, Jenny Wilson, Ming Wei   +4 more
wiley   +1 more source

Emerging experimental and bioinformatic approaches in RNA interference‐based pest control research

Insect Molecular Biology, Volume 35, Issue 4, Page 364-375, August 2026.
Double‐stranded RNA (dsRNA) visualization, RNA‐induced silencing complex (RISC)‐bound sRNA‐seq and RNA degradomics allow investigating dsRNA uptake and processing, guide small interfering RNA selection and RISC‐mediated target mRNA cleavages. Transcriptomic and proteomic profiles of genome‐wide responses to dsRNA, including off‐target and compensatory ...
Doga Cedden
wiley   +1 more source

Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh, Rumpa Banerjee, Hailah M. Almohaimeed, Amany I. Almars, Tahani Ahmad ALMatrafi, Fayez M. Saleh, Zuhair M. Mohammedsaleh, Kranti Kiran Reddy Ealla, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

CaV1.2 dynamics in native male arterial myocytes

The Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel, Hannah Voorhees, Arsalan U. Syed, Maryann K. Ferrara, Mary Horne, Johannes W. Hell, Luis F. Santana, Rose E. Dixon, Madeline Nieves‐Cintron, Manuel F. Navedo   +9 more
wiley   +1 more source

Phosphorylation-dependent structure and dynamics of caveolin-1 8S complex. [PDF]

Biophys J
Karki U, Shabani S, Dahal P, Padilla C, Hutcheson JD, Chapagain P.   +5 more
europepmc   +1 more source

The role of caveolin-1 in atherosclerosis and its molecular mechanism. [PDF]

Lipids Health Dis
Liu X, Wang Z, Liu B, Wang J, Meng Q, Li Y.   +5 more
europepmc   +1 more source

Role of Caveolin-1 in Inflammation: Genetic Predisposition and Potential Implication for Multiple Sclerosis. [PDF]

Genes (Basel)
Getachew B, Miller MR, Landis HE, Miller RE, Tizabi Y.   +4 more
europepmc   +1 more source

Targeting caveolin-1: dual challenges in tumor immunity and drug therapy strategies. [PDF]

Cancer Cell Int
Ge X, Song T, Guo X, Li J, Wang Z, Shi Y, Qin L, Zhang C.   +7 more
europepmc   +1 more source

Correction: Knockdown of MSI2 inhibits metastasis by interacting with caveolin-1 and inhibiting its ubiquitylation in human NF1-MPNST cells. [PDF]

Cell Death Dis
Yang K, Du J, Shi D, Ji F, Ji Y, Pan J, Lv F, Zhang Y.   +7 more
europepmc   +1 more source