Results 141 to 150 of about 65,797 (247)
Screening anticancer peptides performance in organotypic prostate tumor‐stroma 3D models
International Journal of Cancer, Volume 158, Issue 11, Page 2936-2946, 1 June 2026.What's new? Peptide‐based drugs have emerged as promising anticancer therapies for their potential to disrupt protein–protein interactions. In this study, the authors developed a physiomimetic human 3D prostate cancer spheroid model to assess the efficacy of the CAVPENET peptide in inhibiting tumor growth. Upon incubation with CAVPENET, prostate cancer
Bárbara Matos +7 more
wiley +1 more source
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
Journal of Diabetes, Volume 18, Issue 5, May 2026.This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li +5 more
wiley +1 more source
Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells
Cell Proliferation, Volume 59, Issue 5, May 2026.The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li +14 more
wiley +1 more source
Genome biology, 2004 The caveolin gene family has three members in vertebrates: caveolin-1, caveolin-2, and caveolin-3. So far, most caveolin-related research has been conducted in mammals, but the proteins have also been found in other animals, including Xenopus laevis, Fugu rubripes, and Caenorhabditis elegans.
Terence M, Williams, Michael P, Lisanti
openaire +1 more source
Cell Proliferation, Volume 59, Issue 5, May 2026.This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]
, 2018 Gross, Richard W. +4 more
core +2 more sources
Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs. [PDF]
, 2019 Proper axonal growth and guidance is essential for neuron differentiation and development. Abnormal neuronal development due to genetic or epigenetic influences can contribute to neurological and mental disorders such as Down syndrome, Rett syndrome, and
Almenar-Queralt, Angels +8 more
core +1 more source
Caveolin-1 and Caveolin-2 Expression in Mouse Macrophages [PDF]
Journal of Biological Chemistry, 2001 Peter Gargalovic, Ladislav Dory
openaire +1 more source
Decapod iridescent virus 1 (DIV1) enters hematopoietic <i>Cherax quadricarinatus</i> cells via caveola-mediated endocytosis in a pH-dependent manner. [PDF]
J VirolZheng Q +4 more
europepmc +1 more source