Results 171 to 180 of about 57,111 (301)

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

Proceedings of the National Academy of Sciences of the United States of America, 2016
M. Stoeber, P. Schellenberger, C. A. Siebert, C. Leyrat, A. Helenius, Kay Grünewald   +5 more
semanticscholar   +1 more source

Proteomic Atlas of Notochordal Cell‐Derived Extracellular Vesicles Highlights EV‐Specific NF‐κB Modulation and Functional Implications of the Protein Corona

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT The notochord is a central signalling hub during embryonic development. After regression of the notochord, notochordal cells (NCs) reside within the developing intervertebral disc. The NC‐secretome, including matrix, proteins and extracellular vesicles (NC‐EVs), promotes regeneration of degenerate intervertebral discs and cartilage. This study
Josette C. van Maanen, Chantal Voskamp, Frank M. Riemers, Harmjan R. Vos, Anouk Eversdijk, Marije Kleinjan, Menno Bergmeijer, Martijn J. C. van Herwijnen, Stuart C. Howes, Frances C. Bach, Tim J. M. Welting, Christine L. Le Maitre, Guus G. H. van den Akker, Marca H. M. Wauben, Mariana A. Tryfonidou   +14 more
wiley   +1 more source

Caveolin-1 levels associated with coronary artery disease in Chinese participants: a retrospective cohort study. [PDF]

Front Cardiovasc Med
Chen J, Li H, Liang Y, Wang X, Meng Z.
europepmc   +1 more source

Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization

Oncogene, 2016
C. Hwangbo, N. Tae, S. Lee, O. Kim, OK Park, J. Kim, Seung-Hae Kwon, J.-H. Lee   +7 more
semanticscholar   +1 more source

Caveolin-1 and Caveolin-2 Expression in Mouse Macrophages [PDF]

Journal of Biological Chemistry, 2001
Peter Gargalovic, Ladislav Dory
openaire   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function

Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley   +1 more source

Inflammatory cytokines induce caveolin‐1/β‐catenin signalling in rat nucleus pulposus cell apoptosis through the p38 MAPK pathway

Cell Proliferation, 2016
Jianxi Wang, Huajiang Chen, P. Cao, Xiaodong Wu, Fa-Zhi Zang, Liang-Yu Shi, L. Liang, W. Yuan   +7 more
semanticscholar   +1 more source

Membrane Curvature Generation by the Caveolin 8S Complex and the Role of Cholesterol. [PDF]

J Chem Theory Comput
Vasquez Rodriguez SY, Lazaridis T.
europepmc   +1 more source

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen, Jiayan Jiao, Huiling Yang, Tao He   +3 more
wiley   +1 more source