Synthesis of Tetrahydro-β-Carboline-Based Spirocyclic Peptides via Cascade N-Boc Deprotection and Pictet-Spengler Reaction of Tryptophan: Potent Anti-Inflammatory and Anti-Oxidant Activities. [PDF]
Battula S +3 more
europepmc +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Inflammatory and Oxidative Stress Biomarkers in Gingival Crevicular Fluid (GCF) and Serum of Dogs With Gingivitis and Periodontitis. [PDF]
Turgut D, Kurtdede E.
europepmc +1 more source
Applications of Mesenchymal Stromal Cells for Treatment of Diseases
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley +1 more source
Coordinated Transcriptional Repression of CAV1 and CAV2 in Thoracic Aortic Aneurysm: A microRNA Regulatory Network Analysis. [PDF]
Magouliotis DE +9 more
europepmc +1 more source
Caveolin-1 (CAV1) is a structural protein of caveolae involved in lipid homeostasis and endocytosis. Using newly generated pure Balb/C CAV1 null (Balb/CCAV1−/−) mice, CAV1−/− mice from Jackson Laboratories (JAXCAV1−/−), and CAV1−/− mice developed in the ...
G Leong (13724539) +14 more
core
A Subset of Caveolin-1 Interacts with a Fraction of Acyl-CoA:Cholesterol Acyltransferase 1 (ACAT1/SOAT1) at an Endoplasmic Reticulum Subdomain to Attenuate Cholesteryl Ester Biosynthesis. [PDF]
Chang CCY +4 more
europepmc +1 more source
Nanoparticle‐Mediated Therapy for Glioma: Advances and Prospects
Various nanocarriers, including liposomes, dendrimers, exosomes and gold nanoparticles, are designed to penetrate the blood‐brain barrier and deliver chemotherapy, radiotherapy, immunotherapy, gene therapy, phototherapy, magnetic hyperthermia and sonodynamic therapy for glioma.
Wenqian Jiang +5 more
wiley +1 more source

