Results 101 to 110 of about 63,367 (249)
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]
, 2014 The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V. +7 more
core +1 more source
Caveolin-1 in renal disease [PDF]
Scientific Journal of Genetics and Gene Therapy, 2018 Caveolin-1 is the essential structural formation for lipid raft formation. It has been ascribed to several disease processes in humans due to its ubiquitous distribution.
openaire +1 more source
Animal Research and One Health, EarlyView.Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao +12 more
wiley +1 more source
Identifying the role of caveolin-1 and caveolin-2 in cancer cell proliferation and cancer drug resistance [abstract] [PDF]
, 2006 only availableFaculty Mentor: Dr. Grzegorz Sowa, Medical Pharmacology and PhysiologyCaveolae are flask-shaped invaginations of the plasma membrane. Caveolins are the major protein component building these caveolae.
Myears, Hillary E.
core
Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis [PDF]
, 2015 Peritoneal dialysis (PD) is a form of renal replacement therapy whose repeated use can alter dialytic function through induction of epithelial-mesenchymal transition (EMT) and fibrosis, eventually leading to PD discontinuation. The peritoneum from Cav1-/-
Enrique, Calvo +13 more
core +1 more source
BMEMat, EarlyView.ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning +10 more
wiley +1 more source
BMEMat, EarlyView.TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing +6 more
wiley +1 more source
Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]
, 2013 Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di +7 more
core +1 more source
Biological Reviews, EarlyView.ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu +12 more
wiley +1 more source
Full-Length, Glycosylated NSP4 is Localized to Plasma Membrane Caveolae by a Novel Raft Isolation Technique [PDF]
, 2007 Rotavirus NSP4, initially characterized as an endoplasmic reticulum intracellular receptor, is a multifunctional viral enterotoxin that induces diarrhea in murine pups.
Ball, Judith M. +5 more
core +2 more sources