Results 131 to 140 of about 35,385 (262)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities [PDF]

, 2001
Babak Razani, Jeffery A. Engelman, Xiaobo Wang, William Schubert, Xiao Lan Zhang, Carolyn B. Marks, Frank Macaluso, Robert G. Russell, Maomi Li, Richard G. Pestell, Dolores Di Vizio, Harry Hou, Burkhard Kneitz, Guy Lagaud, George J. Christ, Winfried Edelmann, Michael P. Lisanti   +16 more
openalex   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Application of the Mass Spectrometry–High‐Throughput Technique Over the Immunohistochemical Analysis for Human Brain Tumor Diagnosis and Prognosis: Insights Into Biomarkers' Identification for the Case Study of Grade IV Astrocytomas and Meningiomas

Biomedical Chromatography, Volume 39, Issue 9, September 2025.
ABSTRACT Human brain tumors were commonly monitored in hospital/clinical laboratories by immunohistochemistry (IHC) technique, which provides major insights into their classification. However, this technique remains laborious and still shows pitfalls. Therefore, the current study was endeavored to reveal the assets of the application of high‐throughput
Kaouthar Louati, Fatma Kolsi, Manel Mellouli, Hanen Louati, Rim Kallel, Rania Zribi, Mahdi Borni, Leila Sellami Hakim, Amina Maalej, Sirine Choura, Mohamed Chamkha, Sami Sayadi, Zouheir Khemakhem, Tahya Sellami Boudawara, Mohamed Zaher Boudawara, Kaouthar Zribi, Fathi Safta   +16 more
wiley   +1 more source

The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers

, 1999
William S. Garver, Gazi S. Hossain, M.M Winscott, Randall A. Heidenreich   +3 more
openalex   +1 more source

Colocalization and Interaction of Cyclooxygenase-2 with Caveolin-1 in Human Fibroblasts [PDF]

, 2001
Jun‐Yang Liou, Wuguo Deng, Derek W. Gilroy, Song‐Kun Shyue, Kenneth K. Wu   +4 more
openalex   +1 more source

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 6, September 2025.
ABSTRACT An increasing number of individuals are at high risk of type 2 diabetes (T2DM) and its cardiovascular (CV) complications, which challenges healthcare systems with an increased risk of developing CV diseases. Patients with T2DM exhibit a unique cardiac phenotype termed diabetic cardiomyopathy (DCM).
Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson   +11 more
wiley   +1 more source

Caveolin-1 Associates with TRAF2 to Form a Complex That Is Recruited to Tumor Necrosis Factor Receptors [PDF]

, 2001
Xiao Feng, Mary Lou Gaeta, Lisa A. Madge, Jeong-Hee Yang, John R. Bradley, Jordan S. Pober   +5 more
openalex   +1 more source

Enhanced Cytotoxic Effects of Docetaxel‐Loaded Solid Lipid Nanoparticles (SLN‐DTX) on Gastric Adenocarcinoma In Vitro

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 9, September 2025.
Using nanotechnology as a tool for cancer treatment, the solid lipid nanoparticle of docetaxel (SLN‐DTX) promotes toxicity in human gastric adenocarcinoma cells (AGS), reducing viability and proliferation, morphological, and metabolic changes, in addition to immune response alterations.
Laís Vaz‐Costa, Marina Arantes Radicchi, Caterynne Melo Kauffmann, Guilherme Sirimarco de Souza Silveira Tonelli, Igor Oliveira Santos, Kelly Grace Magalhães, Sônia Nair Báo   +6 more
wiley   +1 more source

Caveolin 1-Mediated Regulation of Receptor Tyrosine Kinase-Associated Phosphatidylinositol 3-Kinase Activity by Ceramide

, 2000
Wayne Zundel, Lillian Marie Swiersz, Amato J. Giaccia   +2 more
openalex   +1 more source