Results 131 to 140 of about 63,367 (249)

Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

open access: yesThe FEBS Journal, EarlyView.
Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini   +4 more
wiley   +1 more source

Topographie von Caveolae und Caveolin-1, -2 und -3 im Herz- und Skelettmuskel von Ratten

open access: yes, 2007
Die Topographie von Caveolae und Caveolin -1,-2 und -3 wurde anhand der Natrium Dodecyl Sulfat-Gefrierbruch-Immunzytochemie im Herz – und Skelettmuskel von Ratten untersucht. Caveolin -1, -2 und -3 stellen das Hauptprotein der Caveolae dar.
Weichel, P. (Peter)
core  

Multiple Functions of Caveolin-1 [PDF]

open access: yesJournal of Biological Chemistry, 2002
Pingsheng, Liu   +2 more
openaire   +2 more sources

Emerging experimental and bioinformatic approaches in RNA interference‐based pest control research

open access: yesInsect Molecular Biology, EarlyView.
Double‐stranded RNA (dsRNA) visualization, RNA‐induced silencing complex (RISC)‐bound sRNA‐seq and RNA degradomics allow investigating dsRNA uptake and processing, guide small interfering RNA selection and RISC‐mediated target mRNA cleavages. Transcriptomic and proteomic profiles of genome‐wide responses to dsRNA, including off‐target and compensatory ...
Doga Cedden
wiley   +1 more source

Use of Caveolin-1, Thyroid Transcription Factor-1, and Cytokeratins 7 and 20 in Discriminating Between Primary and Secondary Pulmonary Adenocarcinoma from Breast or Colonic Origin

open access: yesKaohsiung Journal of Medical Sciences, 2007
The objectives of this study were firstly to compare the immunostaining patterns of antibodies against caveolin-1, thyroid transcription factor-1 (TTF-1), cytokeratin 7 (CK7) and cytokeratin 20 (CK20) in primary and secondary pulmonary adenocarcinomas of
Shu-Chuan Tsao   +3 more
doaj   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng   +4 more
wiley   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira   +3 more
wiley   +1 more source

Caveolin-1, breast cancer and ionizing radiation.

open access: yesCancer genomics & proteomics, 2015
Breast cancer (BC) recovery has increased in recent years thanks to efforts of Omics-based research in this field. However, despite the important results obtained, BC remains a complex multifactorial pathology that is difficult to treat appropriately. Caveolin-1 (CAV1), the basic constituent protein of specialized plasma membrane invaginations called ...
Pucci M   +6 more
openaire   +4 more sources

TMEM16A channel signalling microdomains in the regulation of vascular function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]

open access: yes, 2007
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy