In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang+7 more
wiley +1 more source
Caveolin-1 negatively regulates the calcitonin receptor-like receptor and neuroinflammation in a female mouse model of migraine. [PDF]
Zhou Y+11 more
europepmc +1 more source
Knockdown of Caveolin-1 by Antisense Oligonucleotides Impairs Angiogenesis in Vitro and in Vivo,
Cristiana Griffoni+5 more
openalex +1 more source
Interactions of STAT3 with Caveolin-1 and Heat Shock Protein 90 in Plasma Membrane Raft and Cytosolic Complexes [PDF]
Mehul Shah+3 more
openalex +1 more source
The Role of Repeat Skeletal Muscle Biopsy: Indications, Yield and Outcomes
ABSTRACT Introduction/Aims Muscle biopsy performed to investigate weakness and/or pain may be nondiagnostic and prompt repeat biopsy. We determined the indications and yield of rebiopsy. Methods Patients who underwent > 1 muscle biopsy (South Australia, 2000–2023) were identified.
Thomas Khoo+4 more
wiley +1 more source
ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth+2 more
wiley +1 more source
Caveolin-1 Regulates Parathyroid Hormone (PTH)-Related Protein (PTHrP) Actions on PTH Receptor Type 1 in Bone Cells. [PDF]
Heredero-Jiménez S+7 more
europepmc +1 more source
Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1 [PDF]
Anna Caselli+4 more
openalex +1 more source
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens+15 more
wiley +1 more source
Inhibition of the Caveolin-1 pathway promotes apoptosis and overcomes pan-tyrosine kinase inhibitor resistance in hepatocellular carcinoma. [PDF]
Kabir TD+24 more
europepmc +1 more source