Results 31 to 40 of about 24,232,284 (333)
Acta Pharmaceutica Sinica B, 2021 As one of the most important components of caveolae, caveolin-1 is involved in caveolae-mediated endocytosis and transcytosis pathways, and also plays a role in regulating the cell membrane cholesterol homeostasis and mediating signal transduction.
Canyu Yang +6 more
doaj +1 more source
Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis. [PDF]
, 2008 OBJECTIVE: Recent studies have implicated caveolin 1 in the regulation of transforming growth factor beta (TGFbeta) downstream signaling. Given the crucial role of TGFbeta in the pathogenesis of systemic sclerosis (SSc), we sought to determine whether ...
de Almeida, Cecilia J. +6 more
core +2 more sources
Expression of Caveolin-1, Caveolin-2 and Caveolin-3 in Thyroid Cancer and Stroma [PDF]
Pathobiology, 2012 <i>Objective:</i> To study the expression status of caveolin-1, caveolin-2 and caveolin-3 in the epithelial and stromal compartments of conventional papillary thyroid carcinoma (PTC), diffuse sclerosing variant of papillary carcinoma (DSVPC) and anaplastic carcinoma (AC).
Dokyung, Kim +2 more
openaire +2 more sources
Caveolin-1 expression is elevated in claudin-low mammary tumor cells
Cancer Cell International, 2012 Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E +2 more
doaj +1 more source
Multifaceted Functions of Host Cell Caveolae/Caveolin-1 in Virus Infections
Viruses, 2020 Virus infection has drawn extensive attention since it causes serious or even deadly diseases, consequently inducing a series of social and public health problems.
Yifan Xing +5 more
semanticscholar +1 more source
Journal of Lipid Research, 2002 The Niemann-Pick C1 (NPC1) protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. In this article, cholesterol transport to caveolin-1 and caveolin-2 containing compartments, such as the trans-Golgi ...
William S. Garver +5 more
doaj +1 more source
Journal of the Egyptian National Cancer Institute, 2017 Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj +1 more source
Aquaporin-4 and caveolin-1 as mediators of fibrinogen-driven cerebrovascular pathology in cerebral amyloid angiopathy. [PDF]
Alzheimers DementAbstract INTRODUCTION Cerebral amyloid angiopathy (CAA), marked by amyloid beta (Aβ) accumulation in perivascular spaces (PVSs), contributes to vascular injury and inflammation in Alzheimer's disease. The mechanisms underlying CAA‐related vascular pathology remain unclear.
Singh V +7 more
europepmc +2 more sources
Caveolin-1 Signaling in Lung Fibrosis [PDF]
The Open Rheumatology Journal, 2012 Caveolin-1 is a master regulator of several signaling cascades because it is able to bind to and thereby inhibit members of a variety of kinase families. While associated with caveolae and involved in their generation, caveolin-1 is also present at other sites.
Tourkina, Elena, Hoffman, Stanley
openaire +2 more sources
The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes [PDF]
, 2010 Adipose tissue lipoatrophy caused by caveolin gene deletion in mice is not linked to defective adipocyte differentiation. We show that adipose tissue development cannot be rescued by endothelial specific caveolin-1 re-expression, indicating primordial ...
C. Prado +8 more
core +2 more sources