Results 41 to 50 of about 35,385 (262)
Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear
Molecular Medicine, 2023 Background Caveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty infiltration.
Shanhong Fang +3 more
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Caveolin-1 in sarcomas: friend or foe?
Oncotarget, 2011 Sarcomas represent a heterogeneous group of tumors with a complex and difficult reproducible classification. Their pathogenesis is poorly understood and there are few effective treatment options for advanced disease. Caveolin-1 is a multifunctional scaffolding protein with multiple binding partners that regulates multiple cancer-associated processes ...
Sáinz Jaspeado, Miguel Guillermo +5 more
openaire +5 more sources
Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension
Medical Sciences, 2021 Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH.
Rajamma Mathew
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Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. [PDF]
PLoS ONE, 2013 A multiplicity of vital cellular and tissue level functions are controlled by caveolin-1 and it is considered to be an important candidate for targeted therapeutics.
Min Shao +5 more
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Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond [PDF]
Frontiers in Immunology, 2017 Caveolins, encoded by the CAV gene family, are the main protein components of caveolae. In most tissues, caveolin-1 (Cav-1) and caveolin-2 (Cav-2) are co-expressed, and Cav-2 targeting to caveolae depends on the formation of heterooligomers with Cav-1.
openaire +4 more sources
BMC Cancer, 2012 Background To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). Methods The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus ...
Yan Jun +5 more
doaj +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2020 Background. Recently, several studies have demonstrated that caveolin-1 overexpression is involved in apoptosis resistance, angiogenesis, and invasiveness in hepatocellular carcinoma (HCC).
Zhi-Bo Zhang +3 more
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Dermatologica Sinica, 2018 Background: Caveolin-1 (CAV-1) is a key structural and functional membrane protein that is thought to play a role in controlling cellular proliferation and differentiation. Objective: To study the immunohistochemical expression of caveolin-1 in psoriasis
Shereen Farouk Gheida +2 more
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Glycosphingolipid Mediated Caveolin-1 Oligomerization [PDF]
Journal of Glycomics & Lipidomics, 2012 We have previously demonstrated an association between the accumulation of the glycosphingolipid globotriaosylceramide (Gb3) and the loss of high molecular weight oligomers in the aortas of α-galactosidase A-knockout mice, a model of Fabry disease. In the present study the molecular basis for the association between glycosphingolipids and caveolin-1 ...
Liming Shu, James A. Shayman
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Caveolin as a Potential Drug Target for Cardiovascular Protection
Frontiers in Physiology, 2012 Caveolae and caveolin are key players in a number of disease processes. Current research indicates that caveolins play a significant role in cardiovascular disease and dysfunction.
Stephanie L Sellers +2 more
doaj +1 more source