Results 141 to 150 of about 3,741 (219)

The building blocks of caveolae revealed: caveolins finally take center stage. [PDF]

Biochem Soc Trans, 2023
Kenworthy AK.
europepmc   +1 more source

Classification, Structure–Activity Relationship, and Anti‐Osteoarthritis Mechanism of Natural Flavonoids

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang, Shuqi Zheng, Chunlei Hua, Wanze Feng, Zengxia Liu, Yanhong Sun, Minhui Li   +6 more
wiley   +1 more source

Membrane Curvature Generation by the Caveolin 8S Complex and the Role of Cholesterol. [PDF]

J Chem Theory Comput
Vasquez Rodriguez SY, Lazaridis T.
europepmc   +1 more source

The Role of Membrane Lipids in the Formation and Function of Caveolae. [PDF]

Cold Spring Harb Perspect Biol, 2023
Kenworthy AK, Han B, Ariotti N, Parton RG.   +3 more
europepmc   +1 more source

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan, Shicui Hong, Xinyue Wang, Yanghang Li, Cai Wang, Yaxiao Liu, Ying Chen, Chen Fang, Yifeng Zheng, Shengqi Wang, Juping Zhang, Neng Wang, Zhiyu Wang   +12 more
wiley   +1 more source

Coordinated Transcriptional Repression of CAV1 and CAV2 in Thoracic Aortic Aneurysm: A microRNA Regulatory Network Analysis. [PDF]

Genes (Basel)
Magouliotis DE, Sicouri S, Androutsopoulou V, Baudo M, Athanasiou T, Avgerinos DV, Skoularigis J, Giamouzis G, Ramlawi B, Xanthopoulos A.   +9 more
europepmc   +1 more source

Nrf2–Keap1 Axis Modulation by Phytofabricated Metal Oxide Nanoparticles in Mesenchymal Stem Cell Lineage Bias

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan, Muhammad Taha, Syed Muhammad Faizan Asghar, Muhammad Raza   +3 more
wiley   +1 more source

Editorial: Mechanisms and novel therapeutic targets and approaches for mitochondrial dysfunction in neurological and cardiovascular diseases. [PDF]

Front Physiol
Li Q, Zhang Q.
europepmc   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng, Xiaowei Nan, Ting Wang, Junyao Xiong, Shuo Zhu, Chengjie Yang, Bibo Zhu, Youhui Si, Shengbo Cao, Jing Ye   +9 more
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source