Results 141 to 150 of about 6,074 (242)
Comprehensive Physiology, Volume 16, Issue 3, June 2026.Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid +5 more
wiley +1 more source
Pharmacological ResearchStatins are drugs that have been widely used to decrease the levels of cholesterol and are usually well tolerated. Increasing evidence suggests that these lipid-lowering drugs can impact the structural and functional integrity of lipid rafts, which are ...
Suditi Karthikeyan +7 more
doaj +1 more source
Screening anticancer peptides performance in organotypic prostate tumor‐stroma 3D models
International Journal of Cancer, Volume 158, Issue 11, Page 2936-2946, 1 June 2026.What's new? Peptide‐based drugs have emerged as promising anticancer therapies for their potential to disrupt protein–protein interactions. In this study, the authors developed a physiomimetic human 3D prostate cancer spheroid model to assess the efficacy of the CAVPENET peptide in inhibiting tumor growth. Upon incubation with CAVPENET, prostate cancer
Bárbara Matos +7 more
wiley +1 more source
Genome biology, 2004 The caveolin gene family has three members in vertebrates: caveolin-1, caveolin-2, and caveolin-3. So far, most caveolin-related research has been conducted in mammals, but the proteins have also been found in other animals, including Xenopus laevis, Fugu rubripes, and Caenorhabditis elegans.
Terence M, Williams, Michael P, Lisanti
openaire +1 more source
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
The Structural Proteins of Membrane Rafts, Caveolins and Flotillins, in Lung Cancer: More Than Just Scaffold Elements. [PDF]
Int J Med Sci, 2023 Saldaña-Villa AK, Lara-Lemus R.
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.Simvastatin synergizes with cisplatin in cisplatin‐resistant cervical cancer cells through suppression of the caveolin‐1‐mediated PI3K/AKT signaling axis. ABSTRACT Cervical cancer treatment is often hindered by the emergence of cisplatin (DDP) resistance. Increasing evidence has indicated that statins possess anti‐tumor and chemosensitization potential
Yujia Zhou +7 more
wiley +1 more source
The building blocks of caveolae revealed: caveolins finally take center stage. [PDF]
Biochem Soc Trans, 2023 Kenworthy AK.
europepmc +1 more source
New aspects of retinal photoreceptor morphology and development in normal and pathological conditions [PDF]
, 2015 Berta, Ágnes Ida
core +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source