Results 211 to 220 of about 71,388 (222)

Cannabinoid 1 (CB1) Receptor - Pharmacology, Role in Pain and Recent Developments in Emerging CB1 Agonists

CNS & Neurological Disorders - Drug Targets, 2011
Cannabinoids are antinociceptive in animal models of acute pain, tissue injury and nerve injury induced nociception and act via their cognate receptors, cannabinoid receptor 1 and 2. This review examines the underlying biology of the endocannabinoids and behavioural, neurophysiological, neuroanatomical evidence supporting the notion of pain modulation ...
Rashmi, Talwar, Vijay Kumar, Potluri
openaire   +2 more sources

Depolarization and Ca2+ downregulate CB1 receptors and CB1-mediated signaling in cerebellar granule neurons

Neuropharmacology, 2006
Presynaptic terminals of cerebellar granule neurons are primary targets of cannabinoids, which act through type 1 G alpha(i/o)-coupled cannabinoid receptors (CB1) to modulate glutamate release. To study CB1 signaling investigators use primary cultures of granule neurons, typically grown in medium supplemented with elevated KCl to improve long-term ...
Mary Lou, Vallano, Carol M, Beaman-Hall, Cuong J, Bui, Frank A, Middleton   +3 more
openaire   +2 more sources

CB1

2018
openaire   +1 more source

CB1 Knockout Mice

Science of Aging Knowledge Environment, 2005
openaire   +1 more source

Cannabinoid CB1 receptor antagonists

Drug Development Research, 2009
openaire   +1 more source

CB1 bitopics

openaire   +1 more source

CB1-CB112

openaire   +1 more source

CB1 Cannabinoid Receptor Antagonists

2005
openaire   +1 more source

Non-CB1, Non-CB2 Receptors for Endocannabinoids

2005
V Di Marzo, L De Petrocellis
openaire   +4 more sources

CB1 Blockade and Hypertension

2008
openaire   +1 more source