Results 161 to 170 of about 10,682 (172)

Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy

Bioorganic and Medicinal Chemistry Letters, 2011
Michael D Leitl
exaly  

Crystal Structure of the Human Cannabinoid Receptor CB1

Cell, 2016
Tian Hua, Mengchen Pu, Lu Qu
exaly  

Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists

Bioorganic and Medicinal Chemistry Letters, 2006
Chaofeng
exaly  

1-Benzhydryl-3-phenylurea and 1-Benzhydryl-3-phenylthiourea Derivatives:  New Templates among the CB1 Cannabinoid Receptor Inverse Agonists

Journal of Medicinal Chemistry, 2005
Giulio Giorgio Muccioli, Johan Wouters
exaly  

Characterization of active and inactive states of CB1 receptor and the differential binding state modulation by cannabinoid agonists, antagonists and inverse agonists

Neuropharmacology, 2010
Sangeetha Gupta, Hemant Kumar
exaly  

Synthesis and Activity of 1,3,5-Triphenylimidazolidine-2,4-diones and 1,3,5-Triphenyl-2-thioxoimidazolidin-4-ones: Characterization of New CB1Cannabinoid Receptor Inverse Agonists/Antagonists

Journal of Medicinal Chemistry, 2006
Giulio Giorgio Muccioli, Johan Wouters
exaly  

Design, synthesis, and structure–activity relationships of indole-3-heterocycles as agonists of the CB1 receptor

Bioorganic and Medicinal Chemistry Letters, 2011
Darren P Edwards
exaly  

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities

Philosophical Transactions of the Royal Society B: Biological Sciences, 2012
Roger G Pertwee
exaly  

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

British Journal of Pharmacology, 2007
exaly  

A cryptic pocket in CB1 drives peripheral and functional selectivity

Nature
Vipin Rangari, Evan S O'brien, Kaavya Krishna Kumar   +2 more
exaly