A Critical Evaluation of Terpenoid Signaling at Cannabinoid CB1 Receptors in a Neuronal Model. [PDF]
Molecules, 2022 Dvorakova M +7 more
europepmc +1 more source
Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma
Acta Ophthalmologica, Volume 104, Issue 2, Page 225-232, March 2026.Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner +9 more
wiley +1 more source
Obesity Reviews, Volume 27, Issue 3, March 2026.ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia +5 more
wiley +1 more source
Pharmacologic antagonism of CB1 receptors improves electrophysiological alterations in Purkinje cells exposed to 3-AP. [PDF]
BMC Neurosci, 2023 Ranjbar H +4 more
europepmc +1 more source
EFSA Journal, Volume 24, Issue 3, March 2026.Abstract Following an application from Anxiofit Ltd. pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of Hungary, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked for an opinion on the scientific substantiation of a health claim related to Anxiofit‐1 and reduction of subthreshold and mild ...
EFSA Panel on Nutrition +17 more
wiley +1 more source
Unraveling Endocannabinoid Signaling Pathways in Cisplatin‐Induced Ototoxicity
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.We performed a comprehensive molecular profiling of the endocannabinoid (eCB) system (ECS) in an auditory Hair cell (HC)‐like cell line (1). Afterwards, we developed suitable in vitro and in vivo models of cisplatin‐induced ototoxicity where we identified distinct components of the ECS (CB2R, DAGLβ and ABHD6) as molecular targets of the drug (2 ...
Sakthimala Palaniappan +12 more
wiley +1 more source
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. [PDF]
J Neurosci, 2023 Han X +7 more
europepmc +1 more source
Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors. [PDF]
Mol Pharmacol, 2022 Bosquez-Berger T +8 more
europepmc +1 more source
Electroacupuncture Reduces Anxiety Associated With Inflammatory Bowel Disease By Acting on Cannabinoid CB1 Receptors in the Ventral Hippocampus in Mice. [PDF]
Front Pharmacol, 2022 Hu XF +15 more
europepmc +1 more source
Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia. [PDF]
Biomolecules, 2022 Stark T +10 more
europepmc +1 more source