Results 221 to 230 of about 216,047 (309)

Upper bound limit analysis of coral reef limestone cavern roof stability incorporating a tension‐shear failure mechanism with tensile‐strength cut‐off

open access: yesDeep Underground Science and Engineering, EarlyView.
For the roof of coral reef limestone caverns, a novel tension‐shear composite failure mechanism was developed. The most critical tensile crack model was identified using a hybrid optimization algorithm, and the stability of the cavern roof was analyzed accordingly.
Dongsheng Xu, Chenxu Li, Chuantan Hou
wiley   +1 more source

Explainable hybrid stacking ensemble method for hard rock pillar stability prediction and engineering applications

open access: yesDeep Underground Science and Engineering, EarlyView.
This research proposes an interpretable hybrid stacking ensemble framework, optimized by the Sparrow Search Algorithm, to enhance hard rock pillar stability prediction. By integrating six machine learning models—k‐nearest neighbors, support vector machines, random forests, Gradient Boosting Decision Tree, eXtreme Gradient Boosting, and Light Gradient ...
Ning Wang   +3 more
wiley   +1 more source

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser   +5 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Full moon capsulorhexis, a novel technique: Assessment of surgical outcome in patients of intumescent cataract. [PDF]

open access: yesIndian J Ophthalmol
Sarma SK   +6 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

Cornea Crossword Challenge [CCC]

open access: yesTNOA Journal of Ophthalmic Science and Research
Sivagami Nachiappan   +1 more
doaj   +1 more source

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