Results 1 to 10 of about 61,603 (166)

LOX-A4 shapes Triticum urartu gene pools and contributions to the A subgenome of polyploid wheat [PDF]

Nature Communications
Lipoxygenases (LOXs) play vital roles in plant growth and defense. In this study, through genomic and molecular analyses, we discover a major LOX gene (LOX-A4) differentially expressed in Triticum urartu (Tu), the diploid progenitor of A subgenome in ...
Bei Li, Zhiyong Wang, Lingli Dong, Zhenying Dong, Kunpu Zhang, Yanpeng Wang, Reyazul Rouf Mir, Jinfang Chu, Yiwen Li, Mingtian Zhao, Mengen Chen, Zhaohui Wang, Yue Zhang, Lidan Guo, Annapurna Chitikineni, Jijun Yan, Peiyong Xin, Bingbing Zhang, Junlong Li, Xiao Sun, Yuxuan Meng, Yining Wang, Yanmeng Ding, Jiatian Wang, Shengjia Zhang, Cuilan Shi, Zehong Yan, Shoufen Dai, Weining Song, Caixia Gao, Rajeev K. Varshney, Zhiyong Liu, Daowen Wang, Guangwei Li   +33 more
doaj   +2 more sources

Hydrogen sulfide generated by cystathionine gamma lyase inhibits lysyl oxidase and protects against calcific tendinopathy [PDF]

Journal of Orthopaedic Translation
Background/objective: Increased lysyl oxidase (LOX) activity favors pathologic cartilage and vessel calcification. LOX promotes disease through enhanced collagen cross-linking, inflammation, reactive oxygen species (ROS) production, cell trans ...
Elodie Faure, Ilaria Bernabei, Driss Ehirchiou, Philipp Michel, Daniel Kronenberg, Thomas Pap, Giuseppe Cirino, Richard Stange, Nathalie Busso, Sonia Nasi   +9 more
doaj   +2 more sources

The Potential of Acetylfuran and Furfural from Tamarindus indica as Lipoxygenase Inhibitor: In Silico Study

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2021
Background: Tamarindus indica is a type of plant sub-family Caesalpinioideae, which is predicted to have anti-inflammatory properties. When inflammation occurs, arachidonic acid will undergo metabolism, the LOX pathway will release 5-lipoxygenase (5-LOX).
Apriani Herni Rophi, Yohanes Bare, Dewi Ratih Tirto Sari   +2 more
doaj   +1 more source

Evaluation of Pain on Probing using Anaesthetic Gel in Chronic Periodontitis Patients with True Pressure Sensitive Probe: A Placebo Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Periodontal diagnosis and treatment plan rely on an important aspect which is called as the periodontal probing. However, probing has proven to be a painful procedure especially in untreated chronic periodontitis patients.
Siddani Siva Vara Prasad, Anil Kumar Kancharla, Shareen Babu Perika, Pandranki Divya Deepthi, Anwesh Reddy Nandigam, Mohammad Sheema Tasneem, Billa Sowjanya Reddy, Shruthi Akilandan   +7 more
doaj   +1 more source

Analysis of differential expression of genes of structural and regulatory proteins of connective tissue as factors associated with the vaginal prolapse

Репродуктивная эндокринология, 2023
The article presents data on the differential expression of genes of structural and regulatory proteins of connective tissue (COLIA1, fibronectin, elastin, TGF-β1, LOX) in women with pelvic organ prolapse and stigmas of undifferentiated connective tissue
O.M. Proshchenko, T.O. Govseev, I.B. Ventskivska   +2 more
doaj   +1 more source

The Effect of Diet Supplementation with Pomegranate and Bitter Melon on Lipidomic Profile of Serum and Cancerous Tissues of Rats with Mammary Tumours

Antioxidants, 2020
The aim of this study was to present overall lipid profile of organisms with ongoing neoplastic process and applied diet supplementation with pomegranate seed oil (PSO) and bitter melon extract (BME).
Agnieszka Białek, Małgorzata Jelińska, Małgorzata Białek, Tomasz Lepionka, Małgorzata Czerwonka, Marian Czauderna   +5 more
doaj   +1 more source

Screening for Novel LOX and SOD1 Variants in Keratoconus Patients from Brazil

Journal of Ophthalmic & Vision Research, 2020
Purpose: To investigate the presence of the variants of lysyl oxygenase (LOX) and superoxide dismutase 1 (SOD1) genes in Brazilian patients with advanced keratoconus.
Diego Nery Benevides Gadelha, Alex Felipe Barbosa Feitosa, Rafaela Gomes da Silva, Luana Talita Antunes, Matheus Cavalcanti Muniz, Matheus Alencar de Oliveira, Dáfine de Oliveira Andrade, Nathalia Mayanna da Paz Silva, Sebastião Cronemberger, Bruno Luiz Fonseca Schamber-Reis   +9 more
doaj   +1 more source

Adaptive accuracy enhancement for a simultaneously firing optical position sensor [PDF]

Journal of Sensors and Sensor Systems
An algorithm for adaptive accuracy enhancement of lateral position sensing based on quadrature spatio-temporal modulation is presented, and its application in a prototype micropower optical position sensor with simultaneously firing infrared emitters is ...
E. Burian
doaj   +1 more source

LOX-1, OxLDL, and Atherosclerosis [PDF]

Mediators of Inflammation, 2013
Oxidized low-density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation and progression by several mechanisms, including the induction of endothelial cell activation and dysfunction, macrophage foam cell formation, and smooth muscle cell migration and proliferation.
A. Pirillo, G.D. Norata, A.L. Catapano
openaire   +4 more sources

Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells. [PDF]

PLoS ONE, 2013
Ewing sarcoma is the second most common bone malignancy in children and young adults. It is driven by oncogenic fusion proteins (i.e. EWS/FLI1) acting as aberrant transcription factors that upregulate and downregulate target genes, leading to cellular ...
Noelia Agra, Florencia Cidre, Laura García-García, Juan de la Parra, Javier Alonso   +4 more
doaj   +1 more source