Results 41 to 50 of about 74,325 (301)
Research in Pharmaceutical Sciences, 2016 A family of structurally related LOX enzymes present in human cells which catalyse the metabolism of released arachidonic acid from phospholipids by inflammatory stimuli, to biologically active mediators.
Ahmad Mohammadi-Farani +3 more
doaj +1 more source
High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting. [PDF]
PLoS ONE, 2015 Lysyl oxidase (LOX) has been shown to both promote and suppress tumor progression, but its role in prostate cancer is largely unknown. LOX immunoreactivity was scored in prostate tumor epithelium, tumor stroma and in the tumor-adjacent non-malignant ...
Maria Nilsson +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
La sélection des sites de décharge en Région wallonne [PDF]
Biotechnologie, Agronomie, Société et Environnement, 1999 Landfill site selection in the Walloon Region (Belgium). The systematic approach for landfill site selection, adopted by the Walloon government, is presented, which is planned for the next 20 years.
Lox A., Houtain A.
doaj
Lysyl oxidase-like 3 mRNA expression indicates poor survival from oral squamous cell carcinoma
Journal of Dental Sciences, 2011 Background/purpose: Oral squamous cell carcinoma (OSCC) is highly prevalent worldwide. Lysyl oxidase (LOX) is an important enzyme that modulates the extracellular matrix. The LOX superfamily contains LOX and LOX-like (LOXL) enzymes.
Tzong-Ming Shieh +5 more
doaj +1 more source
LOX expression and functional analysis in astrocytomas and impact of IDH1 mutation. [PDF]
PLoS ONE, 2015 Lysyl oxidase (LOX) is involved in vital biological processes such as cell motility, cell signaling and gene regulation. Deregulation of this protein can contribute to tumor formation and progression. Although it is known that LOX is involved in invasion,
Roseli da Silva +3 more
doaj +1 more source
Diagnostics, 2021 (1) Background: Lysyl oxidase (LOX) plays a dual role in carcinogenesis and studies show a higher risk of cancer in LOX G473A variants. The present study evaluated the pattern of LOX G473A polymorphism (rs1800449) and serum LOX levels in ovarian cancer ...
Suchitra Kumari +4 more
doaj +1 more source
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems
Advanced Materials, EarlyView.DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther +9 more
wiley +1 more source
Improved scFv Anti-LOX-1 Binding Activity by Fusion with LOX-1-Binding Peptides [PDF]
, 2017 The oxidized low-density lipoprotein receptor-1 (LOX-1) targeted single-chain variable fragment (scFvs) is a promising molecule for the targeted delivery of imaging and therapeutic molecules of atherosclerotic diseases; however, its applications are ...
Qiuhong Xie, Wei Hu, Hongyu Xiang
core +1 more source