Results 11 to 20 of about 74,325 (301)
LOX-induced tubulointerstitial fibrosis via the TGF-β/LOX/Snail axis in diabetic mice
Journal of Translational MedicineBackground The partial epithelial-mesenchymal transition (EMT) is emerging as a significant mechanism in diabetic nephropathy (DN). LOX is a copper amine oxidase conventionally thought to act by crosslinking collagen.
Yicheng Lu +4 more
doaj +2 more sources
LOX-1 rewires glutamine ammonia metabolism to drive liver fibrosis
Molecular MetabolismObjective: Liver fibrosis is a crucial condition for evaluating the prognosis of chronic liver disease. Lectin-1ike oxidized low density lipoprotein receptor-1 (LOX-1) has been shown potential research value and therapeutic targeting possibilities in ...
Ruihua Huang +8 more
doaj +2 more sources
RETHINKING EDUCATION: Speech by Lox Pratt, September 2022
, 2023 Teacher: Lox, you can’t do that!Me: Why not?Teacher: Because I say so!Me: Right, this is the big problem. Grown ups still don’t get it. You went to school thirty years ago and you are just carrying on like those teachers you didn’t like back then, who ...
Lox Pratt, Pratt, Lox
core +1 more source
Lox: Protecting the Social Graph in Bridge Distribution [PDF]
, 2022 Access to the open Internet, free from surveillance and censorship, is an important part of fulfilling the right to privacy. Despite this, in many regions of the world, censorship of the Internet is used to limit access to information, monitor the ...
Tulloch, Lindsey
core
LOX-DB—a database on lipoxygenases [PDF]
Bioinformatics, 2003 Abstract Summary: Lipoxygenases are a family of enzymes involved in a variety of human diseases like inflammation, asthma, artherosclerosis and cancer. The lipoxygenases database (LOX-DB) aims to be a web accessible compendium of information in particular on the mammalian members of this multigene family. This resource includes molecular
Thomas Lütteke +3 more
openaire +2 more sources
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
doaj +1 more source
Santa Maria armudu püresinde LOX aktivitesi üzerine bazı katkı maddelerinin inhibisyon etkileri
Journal of Ata-Chem, 2022 Lipoksigenaz (EC 1.13.11.34.; LOX ) enzimleri; yapısında iki ya da daha fazla doymamış bağ bulunduran yağ asitlerini oksitleyen, yapılarında hem grubu bulundurmayan demir taşıyıcı dioksigenazlardır. LOX'lar bitkiler, hayvan dokuları ve siyanobakterilerde
Ömer İrfan Küfrevioğlu +2 more
doaj
4 open, 2019 The anti-hyperglycemic drug, Metformin, is effective in treating early stages of diabetes and has been associated with a 37% decrease in cancer incidence. While the precise mechanisms for the anti-cancer effects of Metformin remain to be elucidated, this
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2. [PDF]
PLoS ONE, 2014 Lipoxygenase (LOX) enzymes catalyze the hydroperoxidation of arachidonic acid and other polyunsaturated fatty acids to hydroxyeicosatetraenoic acids with varying positional specificity to yield important biological signaling molecules.
J Brian Jameson +8 more
doaj +1 more source
Chronic inflammation evoked by pathogenic stimulus during carcinogenesis
4 open, 2019 A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source