Up-regulation of CCL11 and CCL26 is associated with activated eosinophils in bullous pemphigoid
Clinical and Experimental Immunology, 2011 SummaryEosinophils contribute to the pathogenesis of bullous pemphigoid (BP) by secretion of proinflammatory cytokines and proteases. Trafficking of eosinophils into tissue in animal models and asthma depends on interleukin-5 and a family of chemokines named eotaxins, comprising CCL11, CCL24 and CCL26.
Claudia GÜNTHER, G Wozel, Meurer M
exaly +5 more sources
Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults [PDF]
Endocrinology and Metabolism, 2021 Background The C-C motif chemokine ligand 11 (CCL11) has been receiving attention as a potential pro-aging factor. Accordingly, it may be involved in muscle metabolism and sarcopenia, a key component of aging phenotypes.
Da Ae Kim +9 more
doaj +2 more sources
CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age [PDF]
Cells, 2019 CCL11 has recently been shown to differentially affect cell survival under various pathological conditions including stroke. Indeed, CCL11 promotes neuroregeneration in neonatal stroke mice.
Simone Lieschke +10 more
doaj +2 more sources
JHEP Reports, 2023 Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is characterised by accelerated lipid deposition, aberrant inflammation, and excessive extracellular matrix production in the liver.
Zhiwen Fan +9 more
doaj +2 more sources
IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells. [PDF]
PLoS ONE, 2010 Previous findings support the concept that IL-9 may play a significant role in mediating both pro-inflammatory and changes in airway responsiveness that characterizes the atopic asthmatic state. We previously demonstrated that human airway smooth muscle (
Akira Yamasaki +5 more
doaj +2 more sources
CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis [PDF]
Journal of Leukocyte Biology, 2013 ABSTRACTThis study tested the hypothesis that eotaxins (CCL11, CCL24, and CCL26) and IL-5 contribute to eosinophil recruitment to the intestine in UC and that intestinal macrophages are important producers of CCL11 in this disease. Peripheral blood and rectal biopsy samples were obtained from patients with active (n=18) and quiescent UC (n=9), and ...
Maria, Lampinen +4 more
openaire +3 more sources
CCL11 levels in drug-naive bipolar patients: The role of sex and smoking status
Journal of Affective Disorders Reports, 2020 Background: It has been reported that patients with bipolar disorder (BD) present changes in peripheral levels of the inflammatory cytokine CCL11, particularly at latestages.
Flavio Kapczinski +2 more
exaly +3 more sources
Eotaxin-1/CCL11 promotes cellular senescence in human-derived fibroblasts through pro-oxidant and pro-inflammatory pathways [PDF]
Frontiers in Immunology, 2023 IntroductionEotaxin-1/CCL11 is a pivotal chemokine crucial for eosinophil homing to the lungs of asthmatic patients. Recent studies also suggest that CCL11 is involved in the aging process, as it is upregulated in elderly, and correlated with shorter ...
Patrícia Lavandoski +6 more
doaj +3 more sources
CCL11 (Eotaxin) Promotes the Advancement of Aging-Related Cardiovascular Diseases
Reviews in Cardiovascular MedicineAging-related diseases, such as cardiovascular diseases (CVDs), neurodegeneration, cancer, etc., have become important factors that threaten the lifespans of older individuals. A chronic inflammatory response is closely related to aging-related diseases.
Tanwei Zhang +4 more
doaj +3 more sources
IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions.
Yoshitaka Hosokawa +4 more
doaj +4 more sources