Results 21 to 30 of about 13,208 (193)

Role of CCL11 in Eosinophilic Lung Disease during Respiratory Syncytial Virus Infection [PDF]

Journal of Virology, 2005
ABSTRACTRespiratory syncytial virus (RSV) is a major viral pathogen of infants and the elderly. Significant morbidity is caused by an overexuberant mixed lung cell infiltrate, which is thought to be driven by chemokines. One of the main chemotactic mediators responsible for the movement of eosinophils is CCL11 (eotaxin).
Matthews, Stephen P., Tregoning, John S., Coyle, Anthony J., Hussell, Tracy; id_orcid 0000-0001-7186-6141, Openshaw, Peter J M   +4 more
openaire   +4 more sources

Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats. [PDF]

PLoS ONE, 2012
Multiple sclerosis (MS) is a polygenic disease characterized by inflammation and demyelination in the central nervous system (CNS), which can be modeled in experimental autoimmune encephalomyelitis (EAE).
Milena Z Adzemovic, Johan Öckinger, Manuel Zeitelhofer, Sonja Hochmeister, Amennai Daniel Beyeen, Atul Paulson, Alan Gillett, Melanie Thessen Hedreul, Ruxandra Covacu, Hans Lassmann, Tomas Olsson, Maja Jagodic   +11 more
doaj   +2 more sources

SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.

PLoS ONE, 2018
BackgroundFibromyalgia (FM) is a chronic pain syndrome with a high incidence in females that may involve activation of the immune system. We performed exome sequencing on chemokine genes in a region of chromosome 17 identified in a genome-wide family ...
Zhifang Zhang, Jinong Feng, Allen Mao, Keith Le, Deirdre La Placa, Xiwei Wu, Jeffrey Longmate, Claudia Marek, R Paul St Amand, Susan L Neuhausen, John E Shively   +10 more
doaj   +3 more sources

Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement [PDF]

Translational Psychiatry
Postpartum depression (PPD) is linked to neuroimmune dysregulation. Brexanolone, an intravenous formulation of the neurosteroid allopregnanolone and the first FDA-approved treatment for PPD, produces rapid and sustained antidepressant effects.
Irina Balan, Cecilia Isabel Sousa Pearson, Holly Krohn, Todd K. O’Buckley, Kai Xia, Samantha Meltzer-Brody, A. Leslie Morrow, Riah Patterson   +7 more
doaj   +2 more sources

Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis

Iranian Journal of Public Health, 2020
Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI, Hossein KHORRAMDELAZAD, Gholamhossein HASSANSHAHI, Mitra ABBASI FARD, Zahra AHMADI, Mojgan NOROOZI KARIMABAD, Majid MOLLAHOSSEINI   +6 more
doaj   +4 more sources

Analiza stężeń eotaksyny 1/CCL11, eotaksyny 2/CCL24 i eotaksyny 3/CCL26 w surowicy dorosłych chorych na atopowe zapalenie skóry

Przegląd Dermatologiczny, 2011
Introduction. Eosinophils play an important role in development ofallergic diseases. Recent studies indicate their many relevant functionsin the development of allergic inflammation related to both an effectorand immunomodulatory role. The recognition of
Agnieszka Nawrocka, Tomasz Targowski, Elwira Beata Paluchowska, Witold Owczarek   +3 more
doaj   +1 more source

Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling [PDF]

Immunity & Ageing
Background The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective
Sheng Tian, Tianyuan Ye, Chao Tian, Yipeng Zhang, He Li, Hui Shen, Youhua Xu, Xiaorui Cheng   +7 more
doaj   +2 more sources

CCL11 released by GSDMD-mediated macrophage pyroptosis regulates angiogenesis after hindlimb ischemia

Cell Death Discovery
Peripheral vascular disease (PVD) is an emerging public health burden with a high rate of disability and mortality. Gasdermin D (GSDMD) has been reported to exert pyroptosis and play a critical role in the pathophysiology of many cardiovascular diseases.
Yiwen Wang, Yang Gao, Huairui Shi, Rifeng Gao, Ji’e Yang, Ya’nan Qu, Shiyu Hu, Jian Zhang, Jingpu Wang, Jiatian Cao, Feng Zhang, Junbo Ge   +11 more
doaj   +2 more sources

CCL11 and Effects on Pre-osteoclast Migration

, 2017
ABSTRACT  Periodontitis is a chronic inflammatory disease due to dental bacteria, and the disease is highly prevalent worldwide. Both environmental factors and genetic variation are confounding factors. Characteristic for disease development is degradation of gingival tissue and resorption of the alveolar bone due to inflammation.
Lång, Johanna
core   +4 more sources

Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis

Biomedicines
Objective: The course of relapsing–remitting multiple sclerosis (RRMS) is highly variable and there is a lack of effective prognostic biomarkers. This study aimed to assess the potential prognostic value of the chemokines B lymphocyte chemoattractant ...
Işıl Peker, Hacer Eroğlu İçli, Belgin Mutluay, Burcu Yüksel, Zeynep Özdemir, Mesrure Köseoğlu, Aysu Şen, Dilek Ataklı, Aysun Soysal, Musa Öztürk   +9 more
doaj   +3 more sources