Results 181 to 190 of about 100,458 (303)

Diagnostic Usefulness of SP-D, CCL2/MCP-1, and IL-18 in Assessing Respiratory Function and Risk of Pulmonary Fibrosis in COVID-19 Patients. [PDF]

Int J Mol Sci
Cylwik B, Gan K, Kazberuk M, Gruszewska E, Panasiuk A, Sienkiewicz M, Wojtkowska M, Chrostek L.   +7 more
europepmc   +1 more source

MAIT Cells Maintain Intestinal Homeostasis Through IL-22 in an Experimental Colitis. [PDF]

J Inflamm Res
Peng Y, Zheng C, Wang Y, Huang F, Shao Y, Liu L, Zhao Q.   +6 more
europepmc   +1 more source

Cessation of CCL2 Inhibition Precipitates Breast Cancer Metastases and Death

, 2014
Here we report a paradoxical effect of the CC chemokine ligand 2 (CCL2) in metastatic breast cancer. Secretion of CCL2 by mammary tumors recruits CCR2-expressing inflammatory monocytes to primary tumors and metastatic sites and CCL2 neutralization in ...
coissieux, marie-may, wyckoff, Jeffrey, Mertz, Kirsten D., Junt, Tobias, Bentires-Alj, Mohamed, Bonapace, Laura, Varga, Zsuzsanna   +6 more
core  

Myeloid-Derived Suppressor Cells: Function, Migration, and Therapeutic Opportunities in Glioblastoma. [PDF]

Cells
Figg JW, Love C, West I, Jin D, Engelbart M, Ware D, Bessey R, Flores CT.   +7 more
europepmc   +1 more source

CCL2: A double-edged sword in neuroblastoma, with a critical role in MYCN-amplified tumors. [PDF]

Transl Oncol
Jannot L, Gazeu A, Bendriss-Vermare N, Pochon C, Sartelet H.   +4 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Unraveling the pleiotropic effects of CCR2-dependent signal transduction in fibrosis development. [PDF]

Theranostics
Sun G, Wang J, Tang J, Chen M, Zhang Z, Zhao H, Jin Z, Xu X, Yang Y, Liu J.   +9 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

CCL2 and PAK6 as Candidate Biomarkers of Neuroinflammation in Parkinson's Disease: An Integrated Machine Learning and Single-Nucleus Transcriptomic Study. [PDF]

Brain Sci
Zhu Q, Zhang Z, Zhang L, Li Q, Zhang T, Yang F.   +5 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source