Results 231 to 240 of about 86,321 (247)

CCL2 DNA vaccine to treat renal disease

The International Journal of Biochemistry & Cell Biology, 2009
CCL2 DNA vaccines are directed against the host chemoattractant molecule CCL2 (MCP-1), a key chemokine in recruiting macrophages to sites of inflammation. Macrophages recruited by CCL2 lead to progressive renal injury. In rat models of disease unmodified CCL2 DNA vaccine in combination with a CCL5 (RANTES) DNA vaccine can protect against chronic renal ...
Watson, Debbie, Zheng, Guoping, Wu, Huiling, Wang, Yuan Min, Wang, Yiping, Harris, David C. H, Alexander, S I   +6 more
openaire   +3 more sources

Association of CCL2 Gene Variants with Osteoarthritis

Archives of Medical Research, 2019
The chemokine (C-C motif) Ligand 2 (CCL2)/CCR2 signaling was associated with macrophage accumulation, synovitis and cartilage damage in a mouse osteoarthritis (OA) model.Here a case-control study in a Chinese Han population was conducted to investigate the possible association between the CCL2 gene polymorphism and risk of OA.
Zhonghua, Xu, Jin, Li, Haoyu, Yang, Lifeng, Jiang, Xindie, Zhou, Yong, Huang, Nanwei, Xu   +6 more
openaire   +2 more sources

Fibroblast-Derived CCL2 Induces Cancer Stem Cells—Letter

Cancer Research, 2013
Tsuyada and colleagues ([1][1]) investigated the effects of cancer-associated fibroblasts (CAF) on cancer stem cells (CSC). In contrast to a number of previous studies that focused only on the intrinsic factors, this study is very unique as it characterizes the factors within the ...
Gunaydin, G., Dolen, Y., Kesikli, S.A.
openaire   +3 more sources

Simvastatin reduces CCL2 expression in monocyte-derived cells by induction of a repressive CCL2 chromatin state

Human Immunology, 2014
Statins exert anti-inflammatory characteristics, besides their lipid lowering properties, and may display beneficial effects for the treatment of inflammatory diseases. One possible explanation is that statins interfere in the deregulated gene transcription patterns associated with immune-mediated diseases, although the precise mechanism is not fully ...
Zannette, D.L., van Eggermond, M.C.J.A., Haasnoot, G., van den Elsen, P.J.   +3 more
openaire   +3 more sources

CCl2

2006
E. Hirota, T. Iijima, K. Kuchitsu, D. A. Ramsay, J. Vogt, N. Vogt   +5 more
openaire   +1 more source

CCl2 Dichloromethylene

2005
G. Graner, E. Hirota, T. Iijima, K. Kuchitsu, D. A. Ramsay, J. Vogt, N. Vogt   +6 more
openaire   +1 more source

CCl2S Thiocarbonyl dichloride

2005
G. Graner, E. Hirota, T. Iijima, K. Kuchitsu, D. A. Ramsay, J. Vogt, N. Vogt   +6 more
openaire   +1 more source

APPLICATION OF CCl4 AND CCl2:CCl2 ULTRASONIC MODULATORS TO INFRARED OPTICAL HETERODYNE EXPERIMENTS

Applied Physics Letters, 1966
F. E. Goodwin, M. E. Pedinoff
openaire   +1 more source

8 CCl2 Dichloromethylene

2014
E. Hirota, K. Kuchitsu, T. Steimle, J. Vogt, N. Vogt   +4 more
openaire   +1 more source

10 CCl2S Carbonothioic dichloride

2014
E. Hirota, K. Kuchitsu, T. Steimle, J. Vogt, N. Vogt   +4 more
openaire   +1 more source