Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 10, October 2026.This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
From diet to disease modulation: the multi-targeted effects of medicinal-food homologous plants in hepatic fibrosis. [PDF]
Front NutrChen S +6 more
europepmc +1 more source
Fibro‐Adipogenic Progenitor Ablation Triggers Muscle Atrophy Through Cell Death‐Induced Inflammation
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.ABSTRACT Background Skeletal muscle mass maintenance involves coordination of myofibers with mononuclear cell populations, including satellite cells, resident macrophages and fibro‐adipogenic progenitors (FAPs). FAPs, identified by surface expression of PDGFRα, are important contributors to muscle homeostasis, as genetic ablation of FAPs induces rapid ...
Yangyi E. Luo +5 more
wiley +1 more source
A Preliminary in-vitro Evaluation of Serum Capped Colloidal Silver Nanoparticles on Liver Cancer towards Development of Safe Personalized Nanomedicine. [PDF]
Int J NanomedicineParveen R +5 more
europepmc +1 more source
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
p21-activated kinase 4 drives hepatic stellate cell activation and liver fibrosis through the phosphorylation of YAP at T428. [PDF]
Signal Transduct Target TherKim GH +16 more
europepmc +1 more source
MedComm, Volume 7, Issue 10, October 2026.This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
Ellagic Acid Attenuates CCl<sub>4</sub>-Induced Hepatic Fibrosis and Is Associated with Changes in PI3K/AKT- and EMT-Related Protein Expression. [PDF]
Curr Issues Mol BiolTan D +6 more
europepmc +1 more source
MedComm, Volume 7, Issue 10, October 2026.This prospective single‐arm study evaluated neoadjuvant disitamab vedotin plus penpulimab in 20 patients with Stage II–III HER2‐low breast cancer. The regimen showed preliminary activity (pCR 20.0% intention‐to‐treat, 25.0% evaluable; ORR 56.3%) with manageable toxicity.
Xiaoxiao Liu +17 more
wiley +1 more source