Results 261 to 270 of about 71,715 (302)

Plastid-mediated feedback regulation of Arabidopsis LYCOPENE EPSILON CYCLASE is modulated by the promoter and a 5'UTR structural variant harbouring a conserved IRES. [PDF]

BMC Biol
Alagoz Y, Nayak JJ, Aryal R, Watkins JL, Holland S, Tissue DT, Pogson BJ, Cazzonelli CI.   +7 more
europepmc   +1 more source

Dual Roles of CD147 in Regulating THP-1 Monocyte Migration and MCP-1-Induced Inflammatory Responses. [PDF]

Int J Mol Sci
Intasai N, Sornsuwan K, Juntit OA, Pamonsupornwichit T, Thongheang K, Jantaree P, Tayapiwatana C.   +6 more
europepmc   +1 more source

Macrophages in ventricular remodeling and heart failure: orchestrators of inflammation and repair. [PDF]

Front Immunol
Feng H, Hu W, Liu Y, Xu X, Zhou P, Qu C, Liu Z.   +6 more
europepmc   +1 more source

Exploring Nanoherbal <i>Paraboea leuserensis</i> as a Therapeutic Agent in Traumatic Brain Injury: <i>In Silico</i>, and <i>In Vivo</i> Approaches. [PDF]

Iran J Med Sci
Ilyas S, Cahaya Situmorang P, Ahmad H, Khairani D, Prastyo Wati D, Sawitri Polem W.   +5 more
europepmc   +1 more source

CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity.

Mucosal Immunol
Pun N, Cytlak UM, Lee D, Domingues RG, Cheadle EJ, Forster D, Whiteley C, Honeychurch J, Williams KJ, Graham GJ, Hepworth MR, Travis MA, Illidge TM, Dyer DP.   +13 more
europepmc   +1 more source

Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation

Bartolini R, Sharma D, Wilson GJ, Dunphy G, Cavanagh J, Halawa HA, Cole J, Weidt S, Gardner-Stephen K, Graham GJ.   +9 more
europepmc   +1 more source

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Engineered Macrophage Membrane-Coated Nanoparticles with Enhanced CCR2 Expression Promote Spinal Cord Injury Repair by Suppressing Neuroinflammation and Neuronal death.

Small, 2023
Spinal cord injury (SCI) is a severe neurological disorder characterized by significant disability and limited treatment options. Mitigating the secondary inflammatory response following the initial injury is the primary focus of current research in the ...
Changjiang Gu, Xiangwu Geng, Yicheng Wu, Yuya Dai, Junkai Zeng, Zhenqiang Wang, Huapan Fang, Yanqing Sun, Xiongsheng Chen   +8 more
semanticscholar   +1 more source

Myeloid CCR2 Promotes Atherosclerosis after AKI

Journal of the American Society of Nephrology, 2022
Background The risk of cardiovascular events rises after AKI. Leukocytes promote atherosclerotic plaque growth and instability. We established a model of enhanced remote atherosclerosis after renal ischemia-reperfusion (IR) injury and investigated the underlying inflammatory mechanisms. Methods
Anne M. Hüsing, Vera C. Wulfmeyer, Svenja Gaedcke, Susanne V. Fleig, Song Rong, David DeLuca, Hermann Haller, Roland Schmitt, Sibylle von Vietinghoff   +8 more
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CCR2 Antagonists

Current Topics in Medicinal Chemistry, 2010
Inhibition of CCR2 has been considered as a target for multiple therapeutic diseases including autoimmune disease, atherosclerosis, pain, and metabolic disease, based in part on the critical role this receptor plays on monocyte migration. Numerous companies have reported programs to identify CCR2 antagonists.
Mary, Struthers, Alexander, Pasternak
openaire   +2 more sources