Results 1 to 10 of about 106,788 (300)

CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer

Cancer Biology & Therapy, 2023
Background Oral tongue cancer is an extremely malignant tumor with high rate of lymphatic metastasis. Little is known about its invasion and metastasis mechanisms so far. Methods To clarify the main role of CCL2 in tongue cancer progression, we performed
Yuqing Dong, Shuning Zhang, Shuangyuan Zhao, Ming Xuan, Guiquan Zhu, Zhuang Zhang, Weihua Guo   +6 more
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The Vascular Circadian Clock in Chronic Kidney Disease

Cells, 2021
Chronic kidney disease is associated with extremely high cardiovascular mortality. The circadian rhythms (CR) have an impact on vascular function. The disruption of CR causes serious health problems and contributes to the development of cardiovascular ...
Søren Egstrand, Maria L. Mace, Klaus Olgaard, Ewa Lewin   +3 more
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RELATIONSHIP BETWEEN THE BLOOD LEVELS OF INFLAMMATORY CYTOKINES AND THE NUMBER OF CIRCULATING TUMOR CELLS WITH RESPONSE TO STANDARD CHEMOTHERAPY IN PATIENTS WITH OVARIAN CANCER

Сибирский онкологический журнал, 2021
Introduction. Serum chemokines are inflammatory mediators, which role is shown in the occurrence and progression of a number of malignant tumors. Produced by white blood cells, stem cells, tumor and endothelial cells, chemokines control their movement ...
S. O. Gening, A. A. Rizvanov, T. V. Abakumova, D. R. Dolgova, D. U. Gafurbaeva, A. R. Rakhmatullina, I. I. Antoneeva, T. P. Gening   +7 more
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Molecular markers of cardiac fibrosis after myocardial infarction

Фундаментальная и клиническая медицина, 2022
Aim. To perform a screening for molecular markers of cardiac fibrosis upon myocardial infarction.Materials and Methods. We carried out echocardiography-guided endomyocardial biopsy of affected and intact interventricular septum segments of 7 patients ...
O. L. Barbarash, A. G. Kutikhin, T. B. Pecherina, R. S. Tarasov, V. V. Kashtalap, N. V. Fedorova, L. A. Bogdanov, O. N. Hryachkova, D. Yu. Sedykh   +8 more
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Clinical significance of CCL2 expression in osteosarcoma tissue [PDF]

Zhongguo aizheng zazhi, 2021
Background and purpose: Osteosarcoma is a primary malignant tumor in bone tissue, mainly in adolescents. The prognosis of patients with lung metastasis is poor.
GONG Runze, HU Haiyan
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The Role of Serum CC-Chemokine Ligand 2 (CCL2) in Obesity: A Comparative Study with Normal Subjects [PDF]

BIO Web of Conferences
Excess fat in the visceral area in the form of obesity is associated with metabolic syndrome. Various factors have been identified that contribute to the pathophysiology of obesity-related metabolic diseases, including chronic inflammatory factors and ...
Lestarini Asri, Aryastuti Anak Agung Sri Agung, Witari Ni Putu Diah, Dewi Ni Wayan Erly Sintya   +3 more
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Identification of a novel regulatory pathway for PPARα by RNA-seq characterization of the endothelial cell lipid peroxidative injury transcriptome [PDF]

Open Biology, 2019
Endothelial dysfunction caused by endothelial cell injuries is the initiating factor for atherosclerosis (AS), and lipid peroxidative injury is one of a dominant factor for AS pathogenesis.
Fangfang Dou, Beiling Wu, Lin Sun, Jiulin Chen, Te Liu, Zhihua Yu, Chuan Chen   +6 more
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Expression of a Fungal Lectin in Arabidopsis Enhances Plant Growth and Resistance Toward Microbial Pathogens and a Plant-Parasitic Nematode

Frontiers in Plant Science, 2021
Coprinopsis cinerea lectin 2 (CCL2) is a fucoside-binding lectin from the basidiomycete C. cinerea that is toxic to the bacterivorous nematode Caenorhabditis elegans as well as animal-parasitic and fungivorous nematodes.
Aboubakr Moradi, Mohamed El-Shetehy, Mohamed El-Shetehy, Jordi Gamir, Tina Austerlitz, Paul Dahlin, Krzysztof Wieczorek, Markus Künzler, Felix Mauch   +8 more
doaj   +1 more source

The effect of C–C motif chemokine ligand 2 supplementation on in vitro maturation of porcine cumulus-oocyte complexes and subsequent developmental competence after parthenogenetic activation

Frontiers in Veterinary Science, 2023
Porcine embryos are used for a variety of applications. However, the maturation rate in vitro remains low, and novel in vitro maturation (IVM) techniques that facilitate the collection of mature oocytes are necessary.
Sohee Kim, Sohee Kim, Dongjin Oh, Dongjin Oh, Hyerin Choi, Hyerin Choi, Mirae Kim, Mirae Kim, Lian Cai, Lian Cai, Lian Cai, Ali Jawad, Ali Jawad, Zheng Haomiao, Zheng Haomiao, Joohyeong Lee, Joohyeong Lee, Eunhye Kim, Sang-Hwan Hyun, Sang-Hwan Hyun, Sang-Hwan Hyun   +20 more
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Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer

OncoImmunology, 2018
The tumor microenvironment (TME) represents a significant barrier to creating effective therapies for metastatic colorectal cancer (mCRC). In several malignancies, bone marrow derived CCR2+ inflammatory monocytes (IM) are recruited to the TME by ...
Julie G Grossman, Timothy M Nywening, Brian A Belt, Roheena Z Panni, Bradley A Krasnick, David G DeNardo, William G Hawkins, S Peter Goedegebuure, David C Linehan, Ryan C Fields   +9 more
doaj   +1 more source