Results 201 to 210 of about 54,562 (253)

Chemokine-defined macrophage niches establish spatial organization of tumor immunity. [PDF]

open access: yesNat Immunol
Ghosh S   +8 more
europepmc   +1 more source

The CCL5/CCR5 Axis in Cancer Progression

open access: yesCancers, 2020
Tumor cells can “hijack” chemokine networks to support tumor progression. In this context, the C-C chemokine ligand 5/C-C chemokine receptor type 5 (CCL5/CCR5) axis is gaining increasing attention, since abnormal expression and activity of ...
Donatella Aldinucci   +2 more
exaly   +2 more sources
Some of the next articles are maybe not open access.

Related searches:

The chemokine receptor, CCR5

The International Journal of Biochemistry & Cell Biology, 2004
The chemokine receptor, CCR5, is a G protein coupled receptor responsible for some of the effects of the chemokines CCL3, CCL4 and CCL5. It is also one of the co-receptors for the entry of human immunodeficiency virus-1 (HIV-1) into cells. Regulation of CCR5 number on cells is, therefore, important for determining the infection rate by HIV-1.
Mueller, A., Strange, P. G.
openaire   +3 more sources

Spiropiperidine CCR5 antagonists

Bioorganic & Medicinal Chemistry Letters, 2009
A novel series of CCR5 antagonists has been identified, utilizing leads from high-throughput screening which were further modified based on insights from competitor molecules. Lead optimization was pursued by balancing opposing trends of metabolic stability and potency. Selective and potent analogs with good pharmacokinetic properties were successfully
David M, Rotstein   +17 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy