Expression of CD105 on expanded mesenchymal stem cells does not predict their chondrogenic potential [PDF]
Objective: Total bone marrow-derived mesenchymal stem cell (BMSC) populations differ in their potential to undergo chondrogenesis, with individual BMSCs differing in their chondrogenic capacity.
M A Cleary +2 more
exaly +2 more sources
Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis [PDF]
CD105 and its ligand transforming growth factor beta (TGFbeta) are modulators of angiogenesis, which drives tumour growth and metastasis. Tumour microvessel density (MVD) has proven to be an important determinant of prognosis.
B K Seon, S T O'Dwyer, O'Dwyer S T
exaly +2 more sources
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Endoglin (CD105) Expression in Endometrial Carcinoma
International Journal of Gynecological Pathology, 2003Tumor angiogenesis plays an important role in tumor growth and metastasis. We evaluated endoglin (CD105) as an endothelial marker of angiogenesis in endometrial carcinoma (EC) and its prognostic significance. Fifty-five cases of EC, 10 cases of complex endometrial hyperplasia with atypia (CHA), and 10 cases of simple hyperplasia (SH) were ...
Reda S, Saad +3 more
openaire +2 more sources
Endoglin (CD105) expression in the development of haemorrhoids
European Journal of Clinical Investigation, 2004AbstractBackground Conventional pathogenesis of haemorrhoid emphasized the anchoring connective tissue system, whereas the vascular changes were ignored. The aim of this study was to clarify vascular changes of haemorrhoid disease.Materials and methods Forty‐six samples of grade III and grade IV haemorrhoid tissue were selected for an in vitro study.
Y-C, Chung, Y-C, Hou, A C-H, Pan
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CD105 (Endoglin) Expression on Hematopoietic Stem/Progenitor Cells
Leukemia and Lymphoma, 2001Endoglin (CD105) is a component of the transforming growth factor-beta (TGF-beta) receptor (TGF-betaR) complex. Together with betaglycan, CD105 is considered as a TGF-betaR accessory molecule (also called TGF-betaRIII), but its functions in the receptor-ligand interactions are still poorly understood.
Luca Pierelli +2 more
exaly +4 more sources
CD105/endoglin expression in Gorham disease of bone
Journal of Clinical Pathology, 2009Background: Gorham disease is a rare pathological condition characterised by a proliferation of vascular channels of haematic and lymphatic origin in bone and adjacent soft tissues, which results in a progressive destruction of the involved bone segment ...
A, Franchi +4 more
openaire +2 more sources
Immunodetection and characterisation of soluble CD105-TGFβ complexes
Journal of Immunological Methods, 1998CD105 (endoglin) is a receptor for transforming growth factor beta (TGFbeta). Although methods to measure soluble forms of TGFbeta and CD105 have been published, no assay is available to quantify the receptor-ligand complexes. We describe both an indirect enzyme-linked immunosorbent assay for the quantitation of soluble CD105-TGFbeta1 and the ...
C G, Li +5 more
openaire +2 more sources
Chronic idiopathic myelofibrosis: independent prognostic importance of bone marrow microvascular density evaluated by CD105 (endoglin) immunostaining [PDF]
Microvascular density (MVD) is substantially increased in bone marrow biopsies of patients with chronic idiopathic myelofibrosis (CIMF). CD105, a useful molecule for assessing MVD in various malignancies, is preferentially expressed by recently formed ...
David G Savage +2 more
exaly +2 more sources
Immunohistochemical Grading of Epidural Fibrosis with CD105 Antibody
World Neurosurgery, 2019Grading of epidural fibrosis (EF) is usually performed by histopathologic staining in experimental studies. Immunohistochemical methods for grading are not available in routine practice yet. In our study, the effect of tranexamic acid (TXA), a commonly used hemostatic agent in surgical interventions, was evaluated for use against the development of EF ...
Uzay Erdogan +6 more
openaire +3 more sources
Differential levels of soluble endoglin (CD105) in myeloid malignancies
Journal of Cellular Physiology, 2002AbstractAngiogenesis contributes to disease progression in solid and hematopoietic malignancies, and endoglin (CD105), a component of the transforming growth factor (TGF)‐β receptor complex, is a powerful marker of neovascularization. Elevated amounts of soluble CD105 (sCD105) have been recently identified in selected solid tumors but no data are ...
CALABRO L +8 more
openaire +4 more sources

